Abstract β-Sheet-rich α-synuclein (αS) aggregates characterize Parkinson's disease (PD).
αS was long believed to be a natively unfolded monomer, but recent work suggests it also …

Human fetal and neonatal bilirubin metabolism is centered on 4Z, 15Z-bilirubin IXα (BR) due
to the extremely low BR conjugating capacity of the liver. BR is a unique, highly lipophilic …

α-Synuclein (αS) is a highly abundant neuronal protein that aggregates into β-sheet–rich
inclusions in Parkinson's disease (PD). αS was long thought to occur as a natively unfolded …

Tissue oxygenation throughout life depends on the activity of hemoglobin (Hb) one of the
hemeproteins that binds oxygen in the lungs and secures its delivery throughout the body …

We present a dual modality functional optical coherence tomography and photoacoustic
microscopy (OCT-PAM) system. The photoacoustic modality employs an akinetic optical …

Beta-like globin gene expression is developmentally regulated during life by transcription
factors, chromatin looping and epigenome modifications of the β-globin locus. Epigenome …

Organisms often harbor seemingly redundant proteins. In the bacterium Salmonella enterica
serovar Typhimurium (S. Typhimurium), the RNA chaperones CspC and CspE appear to …

During the past two decades, significant advances have been made in our understanding of
the human fetal and embryonic hemoglobins made possible by the availability of pure …

Researchers have attempted to generate transfusable oxygen carriers to mitigate RBC
supply shortages. In vitro generation of RBCs using stem cells such as hematopoietic stem …

Development in hemoglobin-based oxygen carriers (HBOCs) that may be used as
alternatives to donated blood requires an extensive supply of highly pure hemoglobin (Hb) …