The relationship between type 2 diabetes, NAFLD, and cardiovascular risk

C Caussy, A Aubin, R Loomba - Current diabetes reports, 2021 - Springer
Abstract Purpose of Review Nonalcoholic fatty liver disease (NAFLD) and type 2 diabetes
mellitus (T2DM) are strongly associated. Both also associate with an increased risk of …

Cardiovascular effects of new oral glucose-lowering agents: DPP-4 and SGLT-2 inhibitors

AJ Scheen - Circulation research, 2018 - Am Heart Assoc
Cardiovascular disease (CVD) is a major challenge in the management of type 2 diabetes
mellitus. Glucose-lowering agents that reduce the risk of major cardiovascular events would …

Effects of sodium-glucose cotransporter 2 inhibitors for the treatment of patients with heart failure: proposal of a novel mechanism of action

M Packer, SD Anker, J Butler, G Filippatos… - JAMA …, 2017 - jamanetwork.com
Importance Only 1 class of glucose-lowering agents—sodium-glucose cotransporter 2
(SGLT2) inhibitors—has been reported to decrease the risk of cardiovascular events …

SGLT-2 inhibitors and the risk of infections: a systematic review and meta-analysis of randomized controlled trials

R Puckrin, MP Saltiel, P Reynier, L Azoulay, OHY Yu… - Acta …, 2018 - Springer
Aims There is concern about the infection-related safety profile of sodium–glucose co-
transporter 2 (SGLT-2) inhibitors. We aimed to determine the effect of SGLT-2 inhibitors on …

Comparative safety of the sodium glucose co-transporter 2 (SGLT2) inhibitors: a systematic review and meta-analysis

JR Donnan, CA Grandy, E Chibrikov, CA Marra… - BMJ open, 2019 - bmjopen.bmj.com
Objective To estimate the association between the use of sodium glucose co-transporter-2
(SGLT2) inhibitors and postmarket harms as identified by drug regulatory agencies. Design …

Medical therapy for heart failure caused by ischemic heart disease

IY Elgendy, D Mahtta, CJ Pepine - Circulation research, 2019 - Am Heart Assoc
Patients with heart failure (HF) syndromes have been categorized as those with reduced
ejection fraction (EF) or preserved EF (HFpEF), and ischemia plays a key role in both types …

Sodium-glucose co-transporter 2 inhibitors and cardiovascular outcomes: a systematic review and meta-analysis

MS Usman, TJ Siddiqi, MM Memon… - European journal of …, 2018 - journals.sagepub.com
Background The risks and benefits of sodium-glucose co-transporter 2 (SGLT2) inhibitors on
cardiovascular outcomes have not been well established. We pooled evidence from all …

Mortality and cardiovascular disease in type 1 and type 2 diabetes

T Htay, K Soe, A Lopez-Perez, AHA Doan… - Current cardiology …, 2019 - Springer
Abstract Purpose of Review The aims of this review are to summarize recent data on
mortality and cardiovascular disease (CVD) in type 1 and type 2 diabetes and to determine …

[HTML][HTML] Complementary and alternative medicine for the treatment of diabetes and associated complications: A review on therapeutic role of polyphenols

P Sharma, YA Hajam, R Kumar, S Rai - Phytomedicine Plus, 2022 - Elsevier
Background: Diabetes is one of the most challenging health problems in 21st century. It is a
group of endocrine-metabolic disorder characterized by high glucose level (hyperglycemia) …

Cardiovascular outcomes in trials of new antidiabetic drug classes: a network meta-analysis

Y Fei, MF Tsoi, BMY Cheung - Cardiovascular diabetology, 2019 - Springer
Background Recent trials suggested that glucagon-like peptide-1 receptor agonists (GLP-1
RAs) and sodium-glucose co-transporter-2 (SGLT-2) inhibitors reduced cardiovascular …