Ceramides are involved in a variety of cellular processes and in disease. Their biological
functions are thought to depend on ceramides' unique biophysical properties, which …

The use of new sophisticated and highly surface sensitive techniques as synchrotron based
X-ray scattering techniques and in-house infrared reflection absorption spectroscopy …

Emerging therapeutic treatments based on the production of proteins by delivering mRNA
have become increasingly important in recent times. While lipid nanoparticles (LNPs) are …

Cholesterol (Chol) is an essential component of animal cell membranes and is most
abundant in plasma membranes (PMs) where its concentration typically ranges from 10 to …

The formation of atherosclerotic plaques in the blood vessel walls is the result of LDL
particle uptake, and consequently of cholesterol accumulation in macrophage cells. Excess …

One of the hallmarks of Alzheimer's disease is the formation of senile plaques, primarily
consisting of amyloid-(A) peptides. Peptide-membrane and peptide-lipid interactions are …

We have developed a high resolution correlative method involving cryo-soft X-ray
tomography (cryo-SXT) and stochastic optical reconstruction microscopy (STORM), which …

When the biological environment deviates from a narrow range of internal balance, some
substances are crystallized in body fluids and adhere to the surface of human tissues. It …

Crystallization of membrane-embedded components within phospholipid bilayers
represents a distinct class of phase transformation that occurs in structurally organized …

We revisit the important issues of polymorphism, structure, and nucleation of cholesterol·
H2O using first-principles calculations based on dispersion-augmented density functional …