Medicinal chemistry of indole derivatives: Current to future therapeutic prospectives
A Kumari, RK Singh - Bioorganic chemistry, 2019 - Elsevier
Indole is a versatile pharmacophore, a privileged scaffold and an outstanding heterocyclic
compound with wide ranges of pharmacological activities due to different mechanisms of …
compound with wide ranges of pharmacological activities due to different mechanisms of …
A review on diverse heterocyclic compounds as the privileged scaffolds in antimalarial drug discovery
The upward extend of malaria collectively with the emergence of resistance against
predictable drugs has put enormous pressure on public health systems to introduce new …
predictable drugs has put enormous pressure on public health systems to introduce new …
An insight into the medicinal perspective of synthetic analogs of indole: A review
PV Thanikachalam, RK Maurya, V Garg… - European journal of …, 2019 - Elsevier
Heterocycles occupy a salient place in chemistry due to their wide range of activity in the
fields of drug design, photochemistry, agrochemicals, dyes, and so on. Amongst all, indole …
fields of drug design, photochemistry, agrochemicals, dyes, and so on. Amongst all, indole …
Recent progress in biological activities of indole and indole alkaloids
The indole scaffold is found in a wide range of bioactive heterocycles and natural products.
Moreover, the indole moiety is considered as the active principle in several alkaloids such …
Moreover, the indole moiety is considered as the active principle in several alkaloids such …
[HTML][HTML] A brief review of the biological potential of indole derivatives
S Kumar, Ritika - Future Journal of Pharmaceutical Sciences, 2020 - Springer
Background Various bioactive aromatic compounds containing the indole nucleus showed
clinical and biological applications. Indole scaffold has been found in many of the important …
clinical and biological applications. Indole scaffold has been found in many of the important …
Sustainable flow approaches to active pharmaceutical ingredients
The adoption of flow conditions has been the object of growing attention from both academia
and industry. The shift from batch to continuous-flow technology is very stimulating from a …
and industry. The shift from batch to continuous-flow technology is very stimulating from a …
An insight into the recent developments in anti-infective potential of indole and associated hybrids
BS Mathada, SB Somappa - Journal of Molecular Structure, 2022 - Elsevier
Prevention, accurate diagnosis, and effective treatment of infections are the main challenges
in the overall management of infectious diseases. The best example is the ongoing SARs …
in the overall management of infectious diseases. The best example is the ongoing SARs …
[HTML][HTML] Flow-based enzymatic synthesis of melatonin and other high value tryptamine derivatives: A five-minute intensified process
To increase the uptake of biocatalytic processes by industry, it is essential to demonstrate
the reliability of enzyme-based methodologies directly applied to the production of high …
the reliability of enzyme-based methodologies directly applied to the production of high …
[HTML][HTML] Recent progress in the development of indole-based compounds active against malaria, trypanosomiasis and leishmaniasis
PAF Pacheco, MMM Santos - Molecules, 2022 - mdpi.com
Human protozoan diseases represent a serious health problem worldwide, affecting mainly
people in social and economic vulnerability. These diseases have attracted little investment …
people in social and economic vulnerability. These diseases have attracted little investment …
Indole-based melatonin analogues: Synthetic approaches and biological activity
SY Wang, XC Shi, P Laborda - European Journal of Medicinal Chemistry, 2020 - Elsevier
Melatonin is a natural hormone primarily released by the pineal gland that regulates the
sleep-wake cycles. The diverse biological applications of melatonin, together with the need …
sleep-wake cycles. The diverse biological applications of melatonin, together with the need …