Ischaemic heart disease, which often manifests clinically as myocardial infarction (MI),
remains a major cause of mortality worldwide. Despite the development of effective pre …

Cardioprotective strategies aim to salvage myocardium from ischemia/reperfusion injury and
to reduce infarct size and its consequences. Different stimuli, acting at sites remote from the …

Aims Glucose-lowering, glucagon-like peptide-1 (GLP-1) receptor agonists reduce
incidence of major cardiovascular (CV) events in patients with Type 2 diabetes mellitus …

After cardiac ischaemia, a prolonged decrease of coronary microvascular perfusion often
occurs even after flow is restored in an upstream artery. This' no-reflow'phenomenon …

Abstract The Hatter Cardiovascular Institute biennial workshop, originally scheduled for April
2020 but postponed for 2 years due to the Covid pandemic, was organised to debate and …

ATP sensitive potassium channels (KATP) are so named because they open as cellular ATP
levels fall. This leads to membrane hyperpolarization and thus links cellular metabolism to …

Rationale: The signal transduction of remote ischemic conditioning is still largely unknown.
Objective: Characterization of neurohumoral signal transfer and vago-splenic axis in remote …

The benefits of remote ischaemic conditioning (RIC) have been difficult to translate to
humans, when considering traditional outcome measures, such as mortality and heart …

Preconditioning, postconditioning, and remote conditioning of the myocardium enhance the
ability of the heart to withstand a prolonged ischemia/reperfusion insult and the potential to …

Semaglutide, a glucagon-like peptide-1 receptor agonist, is clinically used as a glucose-
lowering and weight loss medication due to its effects on energy metabolism. In heart failure …