[HTML][HTML] Synthesis, Computational Study, and In Vitro α-Glucosidase Inhibitory Action of Thiourea Derivatives Based on 3-Aminopyridin-2(1H)-Ones

Z Shulgau, I Palamarchuk, S Sergazy, A Urazbayeva… - Molecules, 2024 - mdpi.com
Reactions with allyl-, acetyl-, and phenylisothiocyanate have been studied on the basis of 3-
amino-4, 6-dimethylpyridine-2 (1 H)-one, 3-amino-4-phenylpyridine-2-one, and 3-amino-4 …

Synthesis, Molecular Docking, and Hemorheological Activity of New 4-(Thien-2-yl)-3-aminopyridine-2(1H)-one Derivatives

IV Palamarchuk, ZT Shulgau, SD Sergazy… - Russian Journal of …, 2022 - Springer
On the basis of 4-(thien-2-yl)-3-aminopyridine-2 (1 H)-one, the corresponding
chloroacetamide and condensed 1 H-pyrido [2, 3-b][1, 4] oxazine-2 (3H)-one were …

Synthesis, structure and molecular docking of new 4, 5-dihydrothiazole derivatives based on 3, 5-dimethylpyrazole and cytisine and salsoline alkaloids

MK Ibrayev, OA Nurkenov, ZB Rakhimberlinova… - Molecules, 2022 - mdpi.com
The interaction results of 1, 2-dibromo-3-isothiocyanatopropane with some pyrazoles as well
as cytisine and salsoline alkaloids were presented in this paper. It was shown that the …

Synthesis and Intramolecular Cyclization of N-acyl- and N-allyl-N'-(2-oxo-1,2-dihydro-pyridin-3-yl)thiourea

IV Kulakov, OS Nikitina, AS Fisyuk… - Chemistry of …, 2014 - Springer
The reaction of 3-amino-4, 6-dimethylpyridin-2 (1H)-one and 3-amino-4-phenylpyridin-2-one
with acyl isothiocyanates (benzoyl-, 4-bromobenzoyl-, and methacryloyl isothiocyanates) …

Synthesis and Antimicrobial Activity of Phthalide Derivatives of Cytisine, Anabasine, and Salsoline

OA Nurkenov, SD Fazylov, ZS Nurmaganbetov… - Chemistry of Natural …, 2023 - Springer
Aminophthalide derivatives of cytisine, anabasine, and salsoline were obtained in high
yields via condensation of the alkaloids with o-formylbenzoic acid. Their structures were …

Synthesis of N-Derivatives of Cytisine, Anabasine, and Salsoline Alkaloids with Pharmacophore 3-Aminopyridine-2(1H)-one and 5-Methyl-7-phenyloxazole[5,4-b] …

IV Palamarchuk, DN Ogurtsova, TM Seilkhanov… - Russian Journal of …, 2019 - Springer
The reaction of nucleophilic substitution of 2-chloro-N-(6-methyl-2-oxo-4-phenyl-1, 2-
dihydropyridin-3-yl) acetamide and 2-(chloromethyl)-5-methyl-7-phenyloxazolo [5, 4-b] …

Amines, amides, and thio-and carboxamides of (–)-cytisine as NFAT transcription factor modulators

YV Vakhitova, IP Tsypysheva, MK Salimgareeva… - Chemistry of natural …, 2014 - Springer
A library of derivatives of the quinolizidine alkaloid (–)-cytisine with amine, amide, and thio-
and carboxamides in the 3-, 5-, and 12-positions were synthesized. Their activity with …

Thioanalogues of N-1-methylanabasine and nicotine–synthesis and structure

M Wojciechowska-Nowak, W Boczoń… - Journal of Molecular …, 2011 - Elsevier
The synthesis, spectral characteristics and structures of N-1-methyl-6-(pyridin-3-yl)
piperidine-2-thione (1)(thioanalogue of N-1-methylanabasine) and N-1-methyl-(5-pyridin-3 …

Synthesis, Characterization, DFT Calculations and Anticoagulant Activity of Symmetrical and Unsymmetrical N-Aryl Thiourea Derivatives.

R Nabti, N Belboukhari, K Sekkoum… - Journal of the …, 2024 - search.ebscohost.com
The present study reports a methodology for the synthesis of symmetrical and unsymmetrical
thiourea derivatives 1-9, which have been prepared in good overall yields from …

Spectroscopic and X-ray studies of N-methylanabasine complexes with ZnX2 (X= Br, Cl)

M Wojciechowska-Nowak, B Jasiewicz… - Journal of Molecular …, 2011 - Elsevier
Abstract ZnX 2 (X= Br, Cl) complexes with N-methylanabasine have been synthesized and
characterized by elemental analysis and spectroscopic techniques. The complexes are …