Opioid abuse has increased in the last decade, primarily as a result of increased access to
prescription opioids. Physicians are also increasingly administering opioid analgesics for …

This paper is the 28th consecutive installment of the annual review of research concerning
the endogenous opioid system, now spanning over a quarter-century of research. It …

The Fourth Edition of Knobil & Neill continues to serve as a reference aid for research, to
provide the historical context to current research, and most importantly as an aid for …

Pair bonds represent some of the strongest attachments we form as humans. These
relationships positively modulate health and well-being. Conversely, the loss of a spouse is …

Introduction: The aim of this study was to investigate how melatonin administration for 3 days
or 7 days following cerebral ischemia (CI) injury would affect autophagy and, therefore …

Abstract Beta-endorphin (β-END) is an opioid neuropeptide which has an important role in
the development of hypotheses concerning the non-synaptic or paracrine communication of …

Monoaminergic systems are known to be involved in the pathophysiology of
neuropsychiatric disorders and vegetative functions due to their established influence on …

Gold nanoparticles (GNPs) have been widely used in medicine such as imaging, drug
delivery and therapeutics due to their multifunctional properties. Alterations in neuronal …

Background Neurodevelopmental disorders are increasing in prevalence worldwide.
Previous work suggests that exposure to the environmental air pollutant and greenhouse …

The non-medical use of prescription opiates, such as Vicodin® and MSContin®, has
increased dramatically over the past decade. Of particular concern is the rising popularity of …