Solar radiation exposure and outdoor work: an underestimated occupational risk

A Modenese, L Korpinen, F Gobba - International journal of …, 2018 - mdpi.com
A considerably high number of outdoor workers worldwide are constantly exposed for the
majority of their working life to solar radiation (SR); this exposure is known to induce various …

UVC-based photoinactivation as an efficient tool to control the transmission of coronaviruses

SK Bhardwaj, H Singh, A Deep, M Khatri… - Science of The Total …, 2021 - Elsevier
The ongoing COVID-19 pandemic made us re-realize the importance of environmental
disinfection and sanitation in indoor areas, hospitals, and clinical rooms. UVC irradiation of …

The effects of exposure to solar radiation on human health

RE Neale, RM Lucas, SN Byrne, L Hollestein… - Photochemical & …, 2023 - Springer
This assessment by the Environmental Effects Assessment Panel (EEAP) of the Montreal
Protocol under the United Nations Environment Programme (UNEP) evaluates the effects of …

[HTML][HTML] Melatonin inhibits ferroptosis and delays age-related cataract by regulating SIRT6/p-Nrf2/GPX4 and SIRT6/NCOA4/FTH1 pathways

Y Mi, C Wei, L Sun, H Liu, J Zhang, J Luo, X Yu… - Biomedicine & …, 2023 - Elsevier
Background Cataracts are the main cause of reversible blindness worldwide. The ageing of
the lens caused by ultraviolet B (UVB) radiation is mostly related to oxidative stress (OS) …

[HTML][HTML] Current insights and future perspectives of ultraviolet radiation (UV) exposure: Friends and foes to the skin and beyond the skin

X Tang, T Yang, D Yu, H Xiong, S Zhang - Environment International, 2024 - Elsevier
Ultraviolet (UV) radiation is ubiquitous in the environment, which has been classified as an
established human carcinogen. As the largest and outermost organ of the body, direct …

α-Crystallins in the vertebrate eye lens: Complex oligomers and molecular chaperones

MA Sprague-Piercy, MA Rocha… - Annual review of …, 2021 - annualreviews.org
α-Crystallins are small heat-shock proteins that act as holdase chaperones. In humans, αA-
crystallin is expressed only in the eye lens, while αB-crystallin is found in many tissues. α …

[HTML][HTML] Cataractogenic load–a concept to study the contribution of ionizing radiation to accelerated aging in the eye lens

A Uwineza, AA Kalligeraki, N Hamada, M Jarrin… - … Research/Reviews in …, 2019 - Elsevier
Ionizing radiation (IR) damages DNA and other macromolecules, including proteins and
lipids. Most cell types can repair DNA damage and cycle continuously their macromolecules …

Cataract frequency and subtypes involved in workers assessed for their solar radiation exposure: a systematic review

A Modenese, F Gobba - Acta ophthalmologica, 2018 - Wiley Online Library
Cataract is currently the primary cause of blindness worldwide, and one of its main risk
factors is solar ultraviolet radiation exposure. According to the localization of lens opacities …

Imbalances in the eye lens proteome are linked to cataract formation

PWN Schmid, NCH Lim, C Peters, KC Back… - Nature Structural & …, 2021 - nature.com
The prevalent model for cataract formation in the eye lens posits that damaged crystallin
proteins form light-scattering aggregates. The α-crystallins are thought to counteract this …

Lens aquaporins function as peroxiporins to facilitate membrane transport of hydrogen peroxide

K Varadaraj, SS Kumari - Biochemical and biophysical research …, 2020 - Elsevier
High levels of reactive oxygen species such as hydrogen peroxide (H 2 O 2) cause oxidative
stress in the lens and lead to cataractogenesis. The present investigation was undertaken to …