Chrysin: Perspectives on contemporary status and future possibilities as pro-health agent

M Stompor-Gorący, A Bajek-Bil, M Machaczka - Nutrients, 2021 - mdpi.com
Chrysin belongs to the group of natural polyphenols. It can be found, among others, in
honey, propolis and fruits and has a wide range of biological activities, including the …

[HTML][HTML] An updated review on the versatile role of chrysin in neurological diseases: Chemistry, pharmacology, and drug delivery approaches

M Talebi, M Talebi, T Farkhondeh… - Biomedicine & …, 2021 - Elsevier
Neurological diseases are responsible for a large number of morbidities and mortalities in
the world. Flavonoids are phytochemicals that possess various health-promoting impacts …

Neuroprotective potential of chrysin: Mechanistic insights and therapeutic potential for neurological disorders

A Mishra, PS Mishra, R Bandopadhyay, N Khurana… - Molecules, 2021 - mdpi.com
Chrysin, a herbal bioactive molecule, exerts a plethora of pharmacological effects, including
anti-oxidant, anti-inflammatory, neuroprotective, and anti-cancer. A growing body of …

Polyphenols: bioavailability, microbiome interactions and cellular effects on health in humans and animals

MB Scott, AK Styring, JSO McCullagh - Pathogens, 2022 - mdpi.com
Polyphenolic compounds have a variety of functions in plants including protecting them from
a range of abiotic and biotic stresses such as pathogenic infections, ionising radiation and …

[HTML][HTML] Interaction of luteolin, naringenin, and their sulfate and glucuronide conjugates with human serum albumin, cytochrome P450 (CYP2C9, CYP2C19, and …

H Kaci, S Bodnárová, E Fliszár-Nyúl, B Lemli… - Biomedicine & …, 2023 - Elsevier
Luteolin and naringenin are flavonoids found in various foods/beverages and present in
certain dietary supplements. After a high intake of these flavonoids, their sulfate and …

[HTML][HTML] Interactions of resveratrol and its metabolites (resveratrol-3-sulfate, resveratrol-3-glucuronide, and dihydroresveratrol) with serum albumin, cytochrome P450 …

M Poór, H Kaci, S Bodnárová, V Mohos… - Biomedicine & …, 2022 - Elsevier
Resveratrol (RES) is a widely-known natural polyphenol which is also contained by several
dietary supplements. Large doses of RES can result in high micromolar levels of its sulfate …

Chrysin attenuates the NLRP3 inflammasome cascade to reduce synovitis and pain in KOA rats

T Liao, L Ding, P Wu, L Zhang, X Li, B Xu… - Drug Design …, 2020 - Taylor & Francis
Purpose Our recent reports have revealed that inhibiting NLRP3 activation reduces synovial
inflammation and fibrosis in knee osteoarthritis (KOA). Synovial inflammation is involved the …

Food antioxidants and their interaction with human proteins

O Nedić, A Penezić, S Minić, M Radomirović, M Nikolić… - Antioxidants, 2023 - mdpi.com
Common to all biological systems and living organisms are molecular interactions, which
may lead to specific physiological events. Most often, a cascade of events occurs …

Protective effects of chrysin against the neurotoxicity induced by aluminium: In vitro and in vivo studies

HM Campos, M da Costa, LK da Silva Moreira… - Toxicology, 2022 - Elsevier
Chronic exposure to aluminium (Al) can contribute to the progression of several neurological
and neurodegenerative diseases. Al is a metal that promotes oxidative damage leading to …

Effects of chrysin and its major conjugated metabolites chrysin-7-sulfate and chrysin-7-glucuronide on cytochrome P450 enzymes and on OATP, P-gp, BCRP, and …

V Mohos, E Fliszár-Nyúl, O Ungvári, É Bakos… - Drug Metabolism and …, 2020 - ASPET
Chrysin is an abundant flavonoid in nature, and it is also contained by several dietary
supplements. Chrysin is highly biotransformed in the body, during which conjugated …