Multimodal machine learning in precision health: A scoping review

A Kline, H Wang, Y Li, S Dennis, M Hutch, Z Xu… - npj Digital …, 2022 - nature.com
Abstract Machine learning is frequently being leveraged to tackle problems in the health
sector including utilization for clinical decision-support. Its use has historically been focused …

[PDF][PDF] Composite pain biomarker signatures for objective assessment and effective treatment

I Tracey, CJ Woolf, NA Andrews - Neuron, 2019 - cell.com
Pain is a subjective sensory experience that can, mostly, be reported but cannot be directly
measured or quantified. Nevertheless, a suite of biomarkers related to mechanisms, neural …

Mapping the heterogeneous phenotype of schizophrenia and bipolar disorder using normative models

T Wolfers, NT Doan, T Kaufmann, D Alnæs… - JAMA …, 2018 - jamanetwork.com
Importance Schizophrenia and bipolar disorder are severe and complex brain disorders
characterized by substantial clinical and biological heterogeneity. However, case-control …

Brain heterogeneity in schizophrenia and its association with polygenic risk

D Alnæs, T Kaufmann, D Van Der Meer… - JAMA …, 2019 - jamanetwork.com
Importance Between-individual variability in brain structure is determined by gene-
environment interactions, possibly reflecting differential sensitivity to environmental and …

A deep learning based model using RNN-LSTM for the Detection of Schizophrenia from EEG data

R Supakar, P Satvaya, P Chakrabarti - Computers in Biology and Medicine, 2022 - Elsevier
Normal life can be ensured for schizophrenic patients if diagnosed early.
Electroencephalogram (EEG) carries information about the brain network connectivity which …

Using structural MRI to identify bipolar disorders–13 site machine learning study in 3020 individuals from the ENIGMA Bipolar Disorders Working Group

A Nunes, HG Schnack, CRK Ching, I Agartz… - Molecular …, 2020 - nature.com
Bipolar disorders (BDs) are among the leading causes of morbidity and disability. Objective
biological markers, such as those based on brain imaging, could aid in clinical management …

Areas of uncertainties and unmet needs in bipolar disorders: clinical and research perspectives

M Bauer, OA Andreassen, JR Geddes… - The Lancet …, 2018 - thelancet.com
This Review discusses crucial areas related to the identification, clinical presentation,
course, and therapeutic management of bipolar disorder, a major psychiatric illness. Bipolar …

Evaluation of risk of bias in neuroimaging-based artificial intelligence models for psychiatric diagnosis: a systematic review

Z Chen, X Liu, Q Yang, YJ Wang, K Miao… - JAMA network …, 2023 - jamanetwork.com
Importance Neuroimaging-based artificial intelligence (AI) diagnostic models have
proliferated in psychiatry. However, their clinical applicability and reporting quality (ie …

The effect of polygenic risk scores for major depressive disorder, bipolar disorder and schizophrenia on morphological brain measures: a systematic review of the …

G Cattarinussi, G Delvecchio, F Sambataro… - Journal of affective …, 2022 - Elsevier
Background Major depressive disorder (MDD), bipolar disorder (BD) and schizophrenia
(SCZ) share clinical features and genetic bases. Magnetic Resonance Imaging (MRI) …

Replicating extensive brain structural heterogeneity in individuals with schizophrenia and bipolar disorder

T Wolfers, J Rokicki, D Alnæs, P Berthet… - Human brain …, 2021 - Wiley Online Library
Identifying brain processes involved in the risk and development of mental disorders is a
major aim. We recently reported substantial interindividual heterogeneity in brain structural …