Motion and uncertainty in radiotherapy is traditionally handled via margins. The clinical
target volume (CTV) is expanded to a larger planning target volume (PTV), which is …

Proton therapy offers dominant advantages over photon therapy due to the unique depth-
dose characteristics of proton, which can cause a dramatic reduction in normal tissue doses …

Purpose To review current evidence of the role of proton therapy (PT) in other tumors than
skull base, sinusal/parasinusal, spinal and pediatric tumors; to determine medico-economic …

Retreatment of recurrent or second primary head and neck cancers occurring in a previously
irradiated field is complex. Few guidelines exist to support practice. We performed an …

Purpose To investigate the impact of setup and range uncertainties, breathing motion, and
interplay effects using scanning pencil beams in robustly optimized intensity modulated …

Particle therapy is rapidly expanding and claiming its position as the treatment modality of
choice in teletherapy. However, the rate of expansion continues to be restricted by the size …

Purpose The development of collimating technologies has become a recent focus in pencil
beam scanning (PBS) proton therapy to improve the target conformity and healthy tissue …

Background and purpose Proton reirradiation for sarcoma has not been previously
described. We hypothesized that this strategy would provide favorable toxicity and survival …

Purpose To compare the difference in robustness of single-field optimized (SFO) and robust
multifield optimized (rMFO) proton plans for oropharynx carcinoma patients by an improved …

Cancers in the head and neck area are usually close to several critical organ structures.
Traditional external-beam photon radiation therapy unavoidably exposes these structures to …