The recent dramatic rise in obesity rates is an alarming global health trend that consumes an
ever increasing portion of health care budgets in Western countries. The root cause of …

Ghrelin, an acylated upper gastrointestinal peptide, is the only known orexigenic hormone.
Considerable evidence implicates ghrelin in mealtime hunger and meal initiation …

Ghrelin is a gastric peptide hormone, discovered as being the endogenous ligand of growth
hormone secretagogue receptor. Ghrelin is a 28 amino acid peptide presenting a unique n …

Ghrelin, a peptide hormone predominantly produced by the stomach, was isolated as the
endogenous ligand for the growth hormone secretagogue receptor. Ghrelin is a potent …

Obesity, diabetes, insulin resistance, sedentary lifestyle, and Western diet are the key factors
underlying non-alcoholic fatty liver disease (NAFLD), one of the most common liver diseases …

Significant advancements have been made in the past century regarding the neuronal
control of feeding behavior and energy expenditure. The effects and mechanisms of action …

Three members of the ghrelin receptor family were characterized in parallel: the ghrelin
receptor, the neurotensin receptor 2 and the orphan receptor GPR39. In transiently …

Among its pleiotropic actions, ghrelin modulates insulin secretion and glucose metabolism.
Herein we investigated the role of ghrelin in pancreatic β-cell proliferation and apoptosis …

Immune and neuroendocrine systems have bidirectional communications. Growth hormone
(GH) and an orexigenic hormone ghrelin are expressed in various immune cells such as T …

BACKGROUND: Ghrelin, an orexigenic 28-amino-acid peptide, has been studied primarily
in relation to the control of appetite and fat metabolism. In addition to these well-known …