Regulation of membrane protein structure and function by their lipid nano-environment
I Levental, E Lyman - Nature Reviews Molecular Cell Biology, 2023 - nature.com
Transmembrane proteins comprise~ 30% of the mammalian proteome, mediating
metabolism, signalling, transport and many other functions required for cellular life. The …
metabolism, signalling, transport and many other functions required for cellular life. The …
Membrane homeostasis beyond fluidity: control of membrane compressibility
Biomembranes are complex materials composed of lipids and proteins that
compartmentalize biochemistry. They are actively remodeled in response to physical and …
compartmentalize biochemistry. They are actively remodeled in response to physical and …
Lipid saturation controls nuclear envelope function
A Romanauska, A Köhler - Nature Cell Biology, 2023 - nature.com
The nuclear envelope (NE) is a spherical double membrane with elastic properties. How NE
shape and elasticity are regulated by lipid chemistry is unknown. Here we discover lipid acyl …
shape and elasticity are regulated by lipid chemistry is unknown. Here we discover lipid acyl …
Systematic design of cell membrane coating to improve tumor targeting of nanoparticles
Cell membrane (CM) coating technology is increasingly being applied in nanomedicine, but
the entire coating procedure including adsorption, rupture, and fusion is not completely …
the entire coating procedure including adsorption, rupture, and fusion is not completely …
Hot topic: Thermosensing in plants
S Hayes, J Schachtschabel, M Mishkind… - Plant, Cell & …, 2021 - Wiley Online Library
Plants alter their morphology and cellular homeostasis to promote resilience under a variety
of heat regimes. Molecular processes that underlie these responses have been intensively …
of heat regimes. Molecular processes that underlie these responses have been intensively …
Low membrane fluidity triggers lipid phase separation and protein segregation in living bacteria
M Gohrbandt, A Lipski, JW Grimshaw… - The EMBO …, 2022 - embopress.org
All living organisms adapt their membrane lipid composition in response to changes in their
environment or diet. These conserved membrane‐adaptive processes have been studied …
environment or diet. These conserved membrane‐adaptive processes have been studied …
Cristae formation is a mechanical buckling event controlled by the inner mitochondrial membrane lipidome
Cristae are high‐curvature structures in the inner mitochondrial membrane (IMM) that are
crucial for ATP production. While cristae‐shaping proteins have been defined, analogous …
crucial for ATP production. While cristae‐shaping proteins have been defined, analogous …
Regulation of immune receptor kinase plasma membrane nanoscale organization by a plant peptide hormone and its receptors
Spatial partitioning is a propensity of biological systems orchestrating cell activities in space
and time. The dynamic regulation of plasma membrane nano-environments has recently …
and time. The dynamic regulation of plasma membrane nano-environments has recently …
Roles of polyunsaturated fatty acids, from mediators to membranes
T Harayama, T Shimizu - Journal of lipid research, 2020 - ASBMB
PUFAs, such as AA and DHA, are recognized as important biomolecules, but understanding
their precise roles and modes of action remains challenging. PUFAs are precursors for a …
their precise roles and modes of action remains challenging. PUFAs are precursors for a …
The ubiquitous role of ubiquitination in lipid metabolism
M Loix, N Zelcer, JFJ Bogie, JJA Hendriks - Trends in Cell Biology, 2024 - cell.com
Lipids are essential molecules that play key roles in cell physiology by serving as structural
components, for storage of energy, and in signal transduction. Hence, efficient regulation …
components, for storage of energy, and in signal transduction. Hence, efficient regulation …