Lysophosphatidylcholine (LPC) is the main component of oxidatively damaged low-density
lipoprotein (oxLDL). LPC originates from the cleavage of phosphatidylcholine by …

Nitric oxide (NO) signalling has pleiotropic roles in biology and a crucial function in
cardiovascular homeostasis. Tremendous knowledge has been accumulated on the …

The Global Burden of Disease Study identified cardiovascular risk factors as leading causes
of global deaths and life years lost. Endothelial dysfunction represents a pathomechanism …

Homocysteine, an amino acid containing a sulfhydryl group, is an intermediate product
during metabolism of the amino acids methionine and cysteine. Hyperhomocysteinemia is …

Objective: The mechanisms involved in NOX5 activation in atherosclerotic processes are not
completely understood. The present study tested the hypothesis that …

Astrocytes express neurotransmitter receptors that serve as sensors of synaptic activity and
initiate signals leading to activity-dependent local vasodilation and increases in blood flow …

Lysophosphatidylcholine (LPC), as the main active component of oxidized low-density
lipoproteins (ox-LDLs), has significant effects in cerebrovascular disease. However, the …

Cardiovascular diseases remain the leading cause of death worldwide for the past 20 years.
Of these, ischemic heart disease has the highest mortality rate. In over 98% of cases it is …

Lysophospholipids (LPLs) are known to have potentially important roles in the initiation and
maintenance of neuropathic pain in animal models. This study investigated the association …

Background: The herbal pairing of Dangshen (DS)[Codonopsis pilosula (Franch.) Nannf.]
and Huangqi (HQ)[Astragalus membranaceus (Fisch.) Bge.](DHP) is a traditional Chinese …