[HTML][HTML] Old World Vipers—a review about snake venom proteomics of Viperinae and their variations

M Damm, BF Hempel, RD Süssmuth - Toxins, 2021 - mdpi.com
Fine-tuned by millions of years of evolution, snake venoms have frightened but also
fascinated humanity and nowadays they constitute potential resources for drug …

[HTML][HTML] Venomics: a mini-review

D Wilson, NL Daly - High-throughput, 2018 - mdpi.com
Venomics is the integration of proteomic, genomic and transcriptomic approaches to study
venoms. Advances in these approaches have enabled increasingly more comprehensive …

Combining in silico and in vitro approaches to identification of potent inhibitor against phospholipase A2 (PLA2)

S Chinnasamy, G Selvaraj, C Selvaraj… - International journal of …, 2020 - Elsevier
Abstract Phospholipase A2 (PLA2) is the main constituent of snake venom. PLA2 enzymes
catalyze the Ca 2+ dependent hydrolysis of 2-acyl ester bonds of 3-sn-phospholipids …

The remarkably enzyme-rich venom of the Big Bend Scorpion (Diplocentrus whitei)

GS Nystrom, SA Ellsworth, DR Rokyta - Toxicon, 2023 - Elsevier
Scorpion venoms have long been studied for their peptide discovery potential, with modern
high-throughput venom-characterization techniques paving the way for the discovery of …

Solenodon genome reveals convergent evolution of venom in eulipotyphlan mammals

NR Casewell, D Petras, DC Card… - Proceedings of the …, 2019 - National Acad Sciences
Venom systems are key adaptations that have evolved throughout the tree of life and
typically facilitate predation or defense. Despite venoms being model systems for studying a …

Composition characterization of various viperidae snake venoms using MS-based proteomics N-glycoproteomics and N-glycomics

MA Aisheh, HM Kayili, YN Cevik, MA Kanat, B Salih - Toxicon, 2023 - Elsevier
Viperidae snake species is widely abundant and responsible for most envenomation cases
in Turkey. The structural and compositional profiles of snake venom have been investigated …

Intact protein mass spectrometry reveals intraspecies variations in venom composition of a local population of Vipera kaznakovi in Northeastern Turkey

D Petras, BF Hempel, B Göçmen, M Karis… - Journal of …, 2019 - Elsevier
We report on the variable venom composition of a population of the Caucasus viper (Vipera
kaznakovi) in Northeastern Turkey. We applied a combination of venom gland …

Toxic activity and protein identification from the parotoid gland secretion of the common toad Bufo bufo

K Kowalski, P Marciniak, G Rosiński… - … and Physiology Part C …, 2018 - Elsevier
Anuran toxins released from the skin glands are involved in defence against predators and
microorganisms. Secretion from parotoid macroglands of bufonid toads is a rich source of …

Investigating the cytotoxic effects of the venom proteome of two species of the Viperidae family (Cerastes cerastes and Cryptelytrops purpureomaculatus) from various …

CS Ozverel, M Damm, BF Hempel, B Göçmen… - … and Physiology Part C …, 2019 - Elsevier
Animal secretions are of great interest in terms of drug development due to their complex
protein and peptide composition. Especially, in the field of therapeutic medications such as …

[HTML][HTML] Phospholipase A2 from krait Bungarus fasciatus venom induces human cancer cell death in vitro

TV Tran, AE Siniavin, AN Hoang, MTT Le, CD Pham… - PeerJ, 2019 - peerj.com
Background Snake venoms are the complex mixtures of different compounds manifesting a
wide array of biological activities. The venoms of kraits (genus Bungarus, family Elapidae) …