Ischaemic conditioning and reperfusion injury
DJ Hausenloy, DM Yellon - Nature Reviews Cardiology, 2016 - nature.com
The 30-year anniversary of the discovery of'ischaemic preconditioning'is in 2016. This
endogenous phenomenon can paradoxically protect the heart from acute myocardial …
endogenous phenomenon can paradoxically protect the heart from acute myocardial …
Extracellular vesicles in diagnostics and therapy of the ischaemic heart: Position Paper from the Working Group on Cellular Biology of the Heart of the European …
Extracellular vesicles (EVs)—particularly exosomes and microvesicles (MVs)—are attracting
considerable interest in the cardiovascular field as the wide range of their functions is …
considerable interest in the cardiovascular field as the wide range of their functions is …
Remote ischemic preconditioning and outcomes of cardiac surgery
DJ Hausenloy, L Candilio, R Evans… - … England Journal of …, 2015 - Mass Medical Soc
Background Whether remote ischemic preconditioning (transient ischemia and reperfusion
of the arm) can improve clinical outcomes in patients undergoing coronary-artery bypass …
of the arm) can improve clinical outcomes in patients undergoing coronary-artery bypass …
Remote ischemic conditioning
In remote ischemic conditioning (RIC), brief, reversible episodes of ischemia with
reperfusion in one vascular bed, tissue, or organ confer a global protective phenotype and …
reperfusion in one vascular bed, tissue, or organ confer a global protective phenotype and …
Ischaemic conditioning and targeting reperfusion injury: a 30 year voyage of discovery
DJ Hausenloy, JA Barrabes, HE Bøtker… - Basic research in …, 2016 - Springer
To commemorate the auspicious occasion of the 30th anniversary of IPC, leading pioneers
in the field of cardioprotection gathered in Barcelona in May 2016 to review and discuss the …
in the field of cardioprotection gathered in Barcelona in May 2016 to review and discuss the …
Critical issues for the translation of cardioprotection
G Heusch - Circulation research, 2017 - Am Heart Assoc
The translation from numerous successful animal experiments on cardioprotection beyond
that by reperfusion to clinical practice has to date been disappointing. Animal experiments …
that by reperfusion to clinical practice has to date been disappointing. Animal experiments …
Cardioprotection by remote ischemic conditioning and its signal transduction
P Kleinbongard, A Skyschally, G Heusch - Pflügers Archiv-European …, 2017 - Springer
Cardioprotective strategies aim to salvage myocardium from ischemia/reperfusion injury and
to reduce infarct size and its consequences. Different stimuli, acting at sites remote from the …
to reduce infarct size and its consequences. Different stimuli, acting at sites remote from the …
Time to give up on cardioprotection? A critical appraisal of clinical studies on ischemic pre-, post-, and remote conditioning
The mortality from acute myocardial infarction (AMI) remains significant, and the prevalence
of post-myocardial infarction heart failure is increasing. Therefore, cardioprotection beyond …
of post-myocardial infarction heart failure is increasing. Therefore, cardioprotection beyond …
ESC Joint Working Groups on Cardiovascular Surgery and the Cellular Biology of the Heart Position Paper: Peri-operative myocardial injury and infarction in patients …
M Thielmann, V Sharma, N Al-Attar… - European heart …, 2017 - academic.oup.com
Coronary artery disease (CAD) is one of the leading causes of death and disability in
Europe and worldwide. For patients with multi-vessel CAD, coronary artery bypass graft …
Europe and worldwide. For patients with multi-vessel CAD, coronary artery bypass graft …
Co‐morbidities and co‐medications as confounders of cardioprotection—Does it matter in the clinical setting?
The translation of cardioprotection from robust experimental evidence to beneficial clinical
outcome for patients suffering acute myocardial infarction or undergoing cardiovascular …
outcome for patients suffering acute myocardial infarction or undergoing cardiovascular …