Natural photosensitizers in antimicrobial photodynamic therapy

E Polat, K Kang - Biomedicines, 2021 - mdpi.com
Health problems and reduced treatment effectiveness due to antimicrobial resistance have
become important global problems and are important factors that negatively affect life …

Hypericin: A natural anthraquinone as promising therapeutic agent

JJ Wu, J Zhang, CY Xia, K Ding, XX Li, XG Pan, JK Xu… - Phytomedicine, 2023 - Elsevier
Background: Hypericin is a prominent secondary metabolite mainly existing in genus
Hypericum. It has become a research focus for a quiet long time owing to its extensively …

Perspectives and trends in the application of photodynamic inactivation for microbiological food safety

VS Ghate, W Zhou, HG Yuk - … in Food Science and Food Safety, 2019 - Wiley Online Library
Photodynamic inactivation is a phenomenon that has the potential to cause microbial
inactivation using visible light. It works on the principle that photosensitizers within the …

Hypericin as a promising natural bioactive naphthodianthrone: A review of its pharmacology, pharmacokinetics, toxicity, and safety

Z Peng, J Lu, K Liu, L Xie, Y Wang, C Cai… - Phytotherapy …, 2023 - Wiley Online Library
Hypericin can be derived from St. John's wort, which is widely spread around the world. As a
natural product, it has been put into clinical practice such as wound healing and depression …

[HTML][HTML] The application of photodynamic inactivation to microorganisms in food

S Zhu, Y Song, J Pei, F Xue, X Cui, X Xiong, C Li - Food Chemistry: X, 2021 - Elsevier
Nowadays, food safety issues have drawn increased attention due to the continual
occurrence of infectious diseases caused by foodborne pathogens, which is an important …

Emerging trends in the photodynamic inactivation (PDI) applied to the food decontamination

M Cossu, L Ledda, A Cossu - Food Research International, 2021 - Elsevier
The food and drink manufacturing industry is constantly seeking for alternative sanitation
and disinfection systems that may achieve the same antimicrobial efficiency of conventional …

The interaction of hypericin with SARS-CoV-2 reveals a multimodal antiviral activity

P Delcanale, E Uriati, M Mariangeli… - … Applied Materials & …, 2022 - ACS Publications
Hypericin is a photosensitizing drug that is active against membrane-enveloped viruses and
therefore constitutes a promising candidate for the treatment of SARS-CoV-2 infections. The …

[HTML][HTML] Advanced theranostic nanoplatforms for hypericin delivery in the cancer treatment

FAP de Morais, RB Balbinot, ABK Bakoshi… - … of Photochemistry and …, 2023 - Elsevier
Biomodified coated-lipid vesicles were obtained using the DPPC lipid (L) and F127
copolymer linked covalently with spermine (SN), biotin (BT), and folic acid (FA), resulting in …

Multifunctional nanoplatforms as a novel effective approach in photodynamic therapy and chemotherapy, to overcome multidrug resistance in cancer

M Majerník, R Jendželovský, J Vargová… - Pharmaceutics, 2022 - mdpi.com
It is more than sixty years since the era of modern photodynamic therapy (PDT) for cancer
began. Enhanced selectivity for malignant cells with a reduced selectivity for non-malignant …

Dissecting the interactions between chlorin e6 and human serum albumin

A Marconi, EJ Mattioli, F Ingargiola, G Giugliano… - Molecules, 2023 - mdpi.com
Chlorin e6 (Ce6) is among the most used sensitizers in photodynamic (PDT) and
sonodynamic (SDT) therapy; its low solubility in water, however, hampers its clinical …