Delirium and dementia are two frequent causes of cognitive impairment among older adults
and have a distinct, complex and interconnected relationship. Delirium is an acute …

Biomarkers of neurodegeneration and neuronal injury have the potential to improve
diagnostic accuracy, disease monitoring, prognosis, and measure treatment efficacy …

Acute respiratory distress syndrome (ARDS) survivors experience a high prevalence of
cognitive impairment with concomitantly impaired functional status and quality of life, often …

Neuroinflammation has become a key hallmark of neurological complications including
perioperative pathologies such as postoperative delirium and longer-lasting postoperative …

Postoperative cognitive dysfunction (POCD) is an objectively measured decline in cognition
postoperatively compared with preoperative function. POCD has been considered in the …

The advancing validation and exploitation of CSF and blood neurofilament light chain
protein as a biomarker of neuroaxonal damage has deeply changed the current diagnostic …

Purpose The development of blood biomarkers that reflect Alzheimer's disease (AD)
pathophysiology (phosphorylated tau and amyloid-β) has offered potential as scalable tests …

Background and purpose Neurological symptoms have been frequently reported in
hospitalized patients with coronavirus disease 2019 (COVID‐19), and biomarkers of central …

Cerebrospinal fluid analyses and neuroimaging can identify the underlying pathophysiology
at the earliest stage of some neurodegenerative disorders, but do not have the scalability …

Cognitive recovery after anaesthesia and surgery is a concern for older adults, their families,
and caregivers. Reports of patients who were 'never the same'prompted a scientific inquiry …