New Findings What is the topic of this review? The manuscript collectively combines the
experimental observations from> 100 publications focusing on the regulation of cerebral …

Cerebral autoregulation (CA) is integral to the delicate process of maintaining stable
cerebral perfusion and brain tissue oxygenation against changes in arterial blood pressure …

Chronic reductions in cerebral blood flow (CBF) and cerebrovascular reactivity to CO 2 are
risk factors for cerebrovascular disease. Higher aerobic fitness is associated with higher …

Quantitative measurements of brain perfusion are influenced by perfusion-modifiers.
Standardization of measurement conditions and correction for important modifiers is …

Current protocols examining cerebral autoregulation (CA) parameters require participants to
refrain from exercise for 12–24 hr, however there is sparse objective evidence examining …

Key points• The influence of normative ageing on cerebral perfusion, oxygenation and
metabolism during exercise is not well known.• This study assessed cerebral perfusion and …

Combined results from different independent studies suggest that acclimatization to high
altitude induces a slowly developing sympathetic activation, even at levels of hypoxia that …

Blood velocity measured in the middle cerebral artery (MCAV) increases with finite kinetics
during moderate-intensity exercise, and the amplitude and dynamics of the response …

A common inclusion criterion when assessing cerebrovascular (CVR) metrics is for
individuals to abstain from exercise for 12–24 hr prior to data collections. While several …

The first accounts of measuring cerebral blood flow (CBF) in humans were made by Angelo
Mosso in~ 1880, who recorded brain pulsations in patients with skull defects. In 1890 …