Mitochondrial and metabolic dysfunction in ageing and age-related diseases
Organismal ageing is accompanied by progressive loss of cellular function and systemic
deterioration of multiple tissues, leading to impaired function and increased vulnerability to …
deterioration of multiple tissues, leading to impaired function and increased vulnerability to …
Molecular pathways of nonalcoholic fatty liver disease development and progression
F Bessone, MV Razori, MG Roma - Cellular and Molecular Life Sciences, 2019 - Springer
Nonalcoholic fatty liver disease (NAFLD) is a main hepatic manifestation of metabolic
syndrome. It represents a wide spectrum of histopathological abnormalities ranging from …
syndrome. It represents a wide spectrum of histopathological abnormalities ranging from …
The effects of probiotics, prebiotics and synbiotics in non-alcoholic fat liver disease (NAFLD) and non-alcoholic steatohepatitis (NASH): A systematic review
RZ Carpi, SM Barbalho, KP Sloan, LF Laurindo… - International journal of …, 2022 - mdpi.com
Modifications in the microbiota caused by environmental and genetic reasons can
unbalance the intestinal homeostasis, deregulating the host's metabolism and immune …
unbalance the intestinal homeostasis, deregulating the host's metabolism and immune …
Exosomes derived from human adipose mesenchymal stem cells ameliorate hepatic fibrosis by inhibiting PI3K/Akt/mTOR pathway and remodeling choline …
Z Zhang, J Shang, Q Yang, Z Dai, Y Liang, C Lai… - Journal of …, 2023 - Springer
Liver fibrosis is a chronic liver disease with the presence of progressive wound healing
response caused by liver injury. Currently, there are no approved therapies for liver fibrosis …
response caused by liver injury. Currently, there are no approved therapies for liver fibrosis …
[HTML][HTML] Oxidative stress, cardiolipin and mitochondrial dysfunction in nonalcoholic fatty liver disease
G Paradies, V Paradies, FM Ruggiero… - World journal of …, 2014 - ncbi.nlm.nih.gov
Nonalcoholic fatty liver disease (NAFLD) is today considered the most common form of
chronic liver disease, affecting a high proportion of the population worldwide. NAFLD …
chronic liver disease, affecting a high proportion of the population worldwide. NAFLD …
Role of oxidative stress in the pathogenesis of nonalcoholic steatohepatitis
The worldwide rising prevalence of obesity and insulin resistance is associated with a
parallel increase in nonalcoholic fatty liver disease (NAFLD). NAFLD is characterized by …
parallel increase in nonalcoholic fatty liver disease (NAFLD). NAFLD is characterized by …
[HTML][HTML] Reactive oxygen species, nutrition, hypoxia and diseases: Problems solved?
A Görlach, EY Dimova, A Petry, A Martínez-Ruiz… - Redox biology, 2015 - Elsevier
Within the last twenty years the view on reactive oxygen species (ROS) has changed; they
are no longer only considered to be harmful but also necessary for cellular communication …
are no longer only considered to be harmful but also necessary for cellular communication …
[HTML][HTML] Mitochondria in non-alcoholic fatty liver disease
ICM Simões, A Fontes, P Pinton, H Zischka… - The international journal …, 2018 - Elsevier
NAFLD is a common disease in Western society and ranges from steatosis to steatohepatitis
and to end-stage liver disease. The molecular mechanisms that cause the progression of …
and to end-stage liver disease. The molecular mechanisms that cause the progression of …
Choline metabolism provides novel insights into nonalcoholic fatty liver disease and its progression
Choline influences liver function, and the dietary requirement for this nutrient varies
depending on an individual's genotype and estrogen status. Understanding these individual …
depending on an individual's genotype and estrogen status. Understanding these individual …
Mitochondria, oxidative stress and nonalcoholic fatty liver disease: A complex relationship
A Karkucinska‐Wieckowska… - European journal of …, 2022 - Wiley Online Library
According to the 'multiple‐hit'hypothesis, several factors can act simultaneously in
nonalcoholic fatty liver disease (NAFLD) progression. Increased nitro‐oxidative (nitroso …
nonalcoholic fatty liver disease (NAFLD) progression. Increased nitro‐oxidative (nitroso …