Stem cells and lung regeneration

KR Parekh, J Nawroth, A Pai… - … of Physiology-Cell …, 2020 - journals.physiology.org
The ability to replace defective cells in an airway with cells that can engraft, integrate, and
restore a functional epithelium could potentially cure a number of lung diseases. Progress …

Insights into the role and potential of Schwann cells for peripheral nerve repair from studies of development and injury

A Balakrishnan, L Belfiore, TH Chu… - Frontiers in Molecular …, 2021 - frontiersin.org
Peripheral nerve injuries arising from trauma or disease can lead to sensory and motor
deficits and neuropathic pain. Despite the purported ability of the peripheral nerve to self …

Synthesis of silver nano particles using myricetin and the in-vitro assessment of anti-colorectal cancer activity: In-silico integration

ST Anwer, M Mobashir, OI Fantoukh, B Khan… - International Journal of …, 2022 - mdpi.com
The creation of novel anticancer treatments for a variety of human illnesses, including
different malignancies and dangerous microbes, also potentially depends on nanoparticles …

Understanding the role of potential pathways and its components including hypoxia and immune system in case of oral cancer

LH Bajrai, SS Sohrab, M Mobashir, MA Kamal… - Scientific Reports, 2021 - nature.com
There are a few biological functions or phenomenon which are universally associated with
majority of the cancers and hypoxia and immune systems are among them. Hypoxia often …

[HTML][HTML] Proneural genes define ground-state rules to regulate neurogenic patterning and cortical folding

S Han, S Okawa, GA Wilkinson, H Ghazale, L Adnani… - Neuron, 2021 - cell.com
Asymmetric neuronal expansion is thought to drive evolutionary transitions between
lissencephalic and gyrencephalic cerebral cortices. We report that Neurog2 and Ascl1 …

A network-guided approach to discover phytochemical-based anticancer therapy: Targeting MARK4 for hepatocellular carcinoma

S Ahmed, M Mobashir, LA Al-Keridis… - Frontiers in …, 2022 - frontiersin.org
MAP/microtubule affinity-regulating kinase 4 (MARK4) is associated with various biological
functions, including neuronal migration, cell polarity, microtubule dynamics, apoptosis, and …

In-Silico study of immune system associated genes in case of type-2 diabetes with insulin action and resistance, and/or obesity

BM Eldakhakhny, H Al Sadoun, H Choudhry… - Frontiers in …, 2021 - frontiersin.org
Type-2 diabetes and obesity are among the leading human diseases and highly complex in
terms of diagnostic and therapeutic approaches and are among the most frequent and …

Modeling heterogeneity in the pluripotent state: A promising strategy for improving the efficiency and fidelity of stem cell differentiation

V Espinosa Angarica, A Del Sol - Bioessays, 2016 - Wiley Online Library
Pluripotency can be considered a functional characteristic of pluripotent stem cells (PSCs)
populations and their niches, rather than a property of individual cells. In this view, individual …

[HTML][HTML] In-silico study reveals immunological signaling pathways, their genes, and potential herbal drug targets in ovarian cancer

PKP Krishnamoorthy, MA Kamal, MK Warsi… - Informatics in Medicine …, 2020 - Elsevier
Ovarian cancer is a leading cause of death due to the fact that most of the patients are
diagnosed at an advanced stage (s) of disease progression because it cannot be detected …

Role of ZNF143 and its association with gene expression patterns, noncoding mutations, and the immune system in human breast cancer

S Saddeek, R Almassabi, M Mobashir - Life, 2022 - mdpi.com
The function of noncoding sequence variations at ZNF143 binding sites in breast cancer
cells is currently not well understood. Distal elements and promoters, also known as cis …