Mechanisms of mechanical overload-induced skeletal muscle hypertrophy: current understanding and future directions
MD Roberts, JJ McCarthy… - Physiological …, 2023 - journals.physiology.org
Mechanisms underlying mechanical overload-induced skeletal muscle hypertrophy have
been extensively researched since the landmark report by Morpurgo (1897) of “work …
been extensively researched since the landmark report by Morpurgo (1897) of “work …
[HTML][HTML] The molecular athlete: exercise physiology from mechanisms to medals
Human skeletal muscle demonstrates remarkable plasticity, adapting to numerous external
stimuli including the habitual level of contractile loading. Accordingly, muscle function and …
stimuli including the habitual level of contractile loading. Accordingly, muscle function and …
Changes in cardiorespiratory fitness and survival in patients with or without cardiovascular disease
Background The association between cardiorespiratory fitness (CRF) and mortality risk is
based mostly on 1 CRF assessment. The impact of CRF change on mortality risk is not well …
based mostly on 1 CRF assessment. The impact of CRF change on mortality risk is not well …
Physiological and molecular sex differences in human skeletal muscle in response to exercise training
Sex differences in exercise physiology, such as substrate metabolism and skeletal muscle
fatigability, stem from inherent biological factors, including endogenous hormones and …
fatigability, stem from inherent biological factors, including endogenous hormones and …
The preconception environment and sperm epigenetics
C Marcho, OA Oluwayiose, JR Pilsner - Andrology, 2020 - Wiley Online Library
Background Infertility is a common reproductive disorder, with male factor infertility
accounting for approximately half of all cases. Taking a paternal perceptive, recent research …
accounting for approximately half of all cases. Taking a paternal perceptive, recent research …
Physical activity is associated with slower epigenetic ageing—Findings from the Rhineland study
Epigenetic ageing, ie, age‐associated changes in DNA methylation patterns, is a sensitive
marker of biological ageing, a major determinant of morbidity and functional decline. We …
marker of biological ageing, a major determinant of morbidity and functional decline. We …
[HTML][HTML] Upstream and downstream regulators of Klotho expression in chronic kidney disease
SS Li, M Sheng, ZY Sun, Y Liang, LX Yu, QF Liu - Metabolism, 2023 - Elsevier
Klotho is a critical protein that protects the kidney. Klotho is severely downregulated in
chronic kidney disease (CKD), and its deficiency is implicated in the pathogenesis and …
chronic kidney disease (CKD), and its deficiency is implicated in the pathogenesis and …
Regular, intense exercise training as a healthy aging lifestyle strategy: preventing DNA damage, telomere shortening and adverse DNA methylation changes over a …
Exercise training is one of the few therapeutic interventions that improves health span by
delaying the onset of age-related diseases and preventing early death. The length of …
delaying the onset of age-related diseases and preventing early death. The length of …
Nucleus type-specific DNA methylomics reveals epigenetic “memory” of prior adaptation in skeletal muscle
Using a mouse model of conditional and inducible in vivo fluorescent myonuclear labeling
(HSA-GFP), sorting purification of nuclei, low-input reduced representation bisulfite …
(HSA-GFP), sorting purification of nuclei, low-input reduced representation bisulfite …
An epigenetic clock for human skeletal muscle
Background Ageing is associated with DNA methylation changes in all human tissues, and
epigenetic markers can estimate chronological age based on DNA methylation patterns …
epigenetic markers can estimate chronological age based on DNA methylation patterns …