In people who are aged> 65 years, pharmacokinetics are influenced more by the loss of
kidney function than by the aging process of any other organ. A GFR of 30 to 60 ml/min …

Program death receptor-1 (PD-1) and program death receptor-1 ligand (PD-L1) inhibitors
are increasingly being used in the clinic to treat a growing number of malignancies …

This article has been corrected. The original version (PDF) is appended to this article as a
supplement. Description: The American College of Physicians (ACP) developed this …

Objectives To compare the patterns of 18 physical and mental health comorbidities between
people with recently diagnosed type 2 diabetes (T2D) and people without diabetes and how …

Predictors and Consequences of Severe Hypoglycemia in Adults with Diabetes –A Systematic
Review of the Evidence Page 1 Evidence-based Synthesis Program Department of Veterans …

Electronic medical records (EMRs) have become a common source of data for outcomes
research. This review discusses trends in EMR data use for outcomes research as well as …

Clinicians are faced with an expansive array of treatment choices when caring for patients
with type 2 diabetes. Because patient compliance may be affected when media …

Drug Class Review Newer Diabetes Medications, TZDs, and Combinations Page 1 Drug Class
Review Newer Diabetes Medications, TZDs, and Combinations Final Original Report February …

Clinical drug trials are often conducted in selective patient populations, with relatively small
numbers of patients, and a short duration of follow-up. Observational studies are therefore …

Objective: To investigate the association between reported oral antidiabetic tolerability
issues and work productivity, activity impairment, and indirect costs. Methods: Data were …