Inborn errors of immunity: A field without frontiers
The study of primary immunodeficiencies or inborn errors of immunity continues to drive our
knowledge of the function of the human immune system. From the outset, the study of inborn …
knowledge of the function of the human immune system. From the outset, the study of inborn …
[HTML][HTML] Elevated IgE Levels—An Allergy or an Underlying Inborn Error of Immunity in Children with Recurrent Infections?
P Kostova, V Papochieva, D Miteva, B Georgieva… - Antibodies, 2023 - mdpi.com
Elevated immunoglobulin E (IgE) is a hallmark of allergic diseases. However, high IgE levels
also occur in a number of other infectious and noninfectious diseases. In most cases …
also occur in a number of other infectious and noninfectious diseases. In most cases …
Anti‐inflammatory control of human skin keratinocytes by targeting nuclear transport checkpoint
Y Liu, H Qiao, J Zienkiewicz… - Skin Health and …, 2024 - Wiley Online Library
Background In the two common inflammatory skin diseases, Atopic Dermatitis (AD) and
Psoriasis (Ps), keratinocytes (KCs) respond to immune insults through activation of …
Psoriasis (Ps), keratinocytes (KCs) respond to immune insults through activation of …
[HTML][HTML] Rapid identification of primary atopic disorders (PAD) by a clinical landmark-guided, upfront use of genomic sequencing
T Niehues, S von Hardenberg, E Velleuer - Allergologie Select, 2024 - ncbi.nlm.nih.gov
Primary atopic disorders (PAD) are monogenic disorders caused by pathogenic gene
variants encoding proteins that are key for the maintenance of a healthy skin barrier and a …
variants encoding proteins that are key for the maintenance of a healthy skin barrier and a …