[HTML][HTML] Engineering mesoporous silica nanoparticles for drug delivery: where are we after two decades?
The present review details a chronological description of the events that took place during
the development of mesoporous materials, their different synthetic routes and their use as …
the development of mesoporous materials, their different synthetic routes and their use as …
Synthetic amorphous silica nanoparticles: toxicity, biomedical and environmental implications
Natural silica and silicates are predominantly crystalline and constitute the most abundant
components of the Earth's crust. Man-made silica is typically amorphous and manufactured …
components of the Earth's crust. Man-made silica is typically amorphous and manufactured …
Mesoporous silica nanoparticles for drug delivery
M Manzano, M Vallet‐Regí - Advanced functional materials, 2020 - Wiley Online Library
In recent years, nanomedicine has emerged at the forefront of nanotechnology, generating
great expectations in the biomedical field. Researchers are developing novel nanoparticles …
great expectations in the biomedical field. Researchers are developing novel nanoparticles …
Mesoporous silica and organosilica nanoparticles: physical chemistry, biosafety, delivery strategies, and biomedical applications
Predetermining the physico‐chemical properties, biosafety, and stimuli‐responsiveness of
nanomaterials in biological environments is essential for safe and effective biomedical …
nanomaterials in biological environments is essential for safe and effective biomedical …
Effect of physicochemical and surface properties on in vivo fate of drug nanocarriers
Over the years, a plethora of materials–natural and synthetic–have been engineered at a
nanoscopic level and explored for drug delivery. Nanocarriers based on such materials …
nanoscopic level and explored for drug delivery. Nanocarriers based on such materials …
Silica-based nanoparticles for biomedical applications: from nanocarriers to biomodulators
Conspectus Silica-based nanoparticles (SNPs) are a classic type of material employed in
biomedical applications because of their excellent biocompatibility and tailorable …
biomedical applications because of their excellent biocompatibility and tailorable …
Degradability and clearance of silicon, organosilica, silsesquioxane, silica mixed oxide, and mesoporous silica nanoparticles
The biorelated degradability and clearance of siliceous nanomaterials have been
questioned worldwide, since they are crucial prerequisites for the successful translation in …
questioned worldwide, since they are crucial prerequisites for the successful translation in …
Nanoparticle–liver interactions: Cellular uptake and hepatobiliary elimination
99% of administered nanoparticles will accumulate and sequester in the liver after
administration into the body. This results in reduced delivery to the targeted diseased tissue …
administration into the body. This results in reduced delivery to the targeted diseased tissue …
Biodistribution, clearance, and long‐term fate of clinically relevant nanomaterials
Realization of the immense potential of nanomaterials for biomedical applications will
require a thorough understanding of how they interact with cells, tissues, and organs. There …
require a thorough understanding of how they interact with cells, tissues, and organs. There …
The toxicity of silica nanoparticles to the immune system
L Chen, J Liu, Y Zhang, G Zhang, Y Kang, A Chen… - …, 2018 - Taylor & Francis
Silicon-based materials and their oxides are widely used in drug delivery, dietary
supplements, implants and dental fillers. Silica nanoparticles (SiNPs) interact with …
supplements, implants and dental fillers. Silica nanoparticles (SiNPs) interact with …