The development of coronary artery disease, and specifically myocardial infarction, involves
hyperplasia of arterial smooth muscle, the development of fatty streaks, atheroma formation …

Plasminogen activator inhibitor-1 (PAI-1), a member of the serine protease inhibitor (serpin)
superfamily with antiprotease activity, is the main physiological inhibitor of tissue-type (tPA) …

Since the first Joint European Societies (European Society of Cardiology, European
Atherosclerosis Society and European Society of Hypertension) Task Force …

There is a common polymorphism in the promoter sequence of the human stromelysin-1
gene, with one allele having a run of six adenosines (6A) and the other five adenosines …

The development of thrombotic disorders in humans is one of the most common causes of
morbidity and mortality in the Western world. Thrombotic disease can be classified in broad …

Summary Plasminogen activator inhibitor-1 (PAI-1), a 45-kDa serine proteinase inhibitor
with reactive site peptide bond Arg345-Met346, is the main physiological plasminogen …

Over the last few years, experimental, cross-sectional and prospective cohort studies have
underlined the association benveen plasma plasminogen activator inhibitor 1 (PAI-l) levels …

BACKGROUND Pre-eclampsia has a clear familial component, suggesting that the condition
may be partly attributable to genetic susceptibility. The search for susceptibility genes has …

Background The concentrations of fibrinogen, factor VII and VIII, von Willebrand factor,
plasminogen activator inhibitor-1 (PAI-1), and tissue plasminogen activator have been …

Background In the context of a comprehensive population strategy to reduce tobacco use,
encourage healthy food choices, and increase physical activity for the whole population, the …