Method of making particles for use in a pharmaceutical composition

JN Staniforth, DAV Morton, R Musa - US Patent 7,744,855, 2010 - Google Patents
(57) ABSTRACT A method for making composite excipient particles for use in a
pharmaceutical composition comprises a milling step in which particles of an excipient …

Pharmaceutical formulations for dry powder inhalers

JN Staniforth, DAV Morton, R Gill, G Brambilla… - US Patent …, 2009 - Google Patents
(57) ABSTRACT A powder for use in a dry powder inhaler comprises: i) a fraction n of fine
particle size constituted by a mixture of physiologically acceptable excipient and an additive; …

Dry Powder Inhaler Formulations Comprising Surface-Modified Particles With Anti-Adherent Additives

D Morton - US Patent App. 11/791,385, 2008 - Google Patents
0001. The present invention is concerned with a refine ment of the processing of particles
that are to form a dry powder formulation which is to be administered to the lung, for example …

Method of making particles for use in a pharmaceutical composition

JN Staniforth, MMJ Green, DAV Morton - US Patent 7,736,670, 2010 - Google Patents
The invention relates to a method for making composite active particles for use in a
pharmaceutical composition for pulmonary administration, the method comprising a milling …

Devices and pharmaceutical compositions for enhancing dosing efficiency

J Staniforth, D Morton, M Tobyn, S Eason… - US Patent App. 10 …, 2006 - Google Patents
2006-03-20 Assigned to VECTURA LTD. reassignment VECTURA LTD. ASSIGNMENT OF
ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors: STANIFORTH …

Pharmaceutical compositions for inhalation

JN Staniforth, H Harris, DAV Morton… - US Patent …, 2011 - Google Patents
The invention provides microparticles for use in a pharma ceutical composition for
pulmonary administration, each microparticle comprising a particle of an active Substance …

Method of therapeutic administration of DHE to enable rapid relief of migraine while minimizing side effect profile

RO Cook, SB Shrewsbury, NN Ramadan… - US Patent …, 2011 - Google Patents
US7994197B2 - Method of therapeutic administration of DHE to enable rapid relief of migraine
while minimizing side effect profile - Google Patents US7994197B2 - Method of therapeutic …

Dry powder composition comprising co-jet milled particles for pulmonary inhalation

D Morton, J Staniforth - US Patent 8,182,838, 2012 - Google Patents
The present invention relates to particles and to methods of making particles. In particular,
the invention relates to meth ods of making composite active particles comprising a phar …

Mucoactive agents for treating a pulmonary disease

D Morton, D Ganderton, J Staniforth… - US Patent 7,928,089, 2011 - Google Patents
The present invention relates to mucoactive agents, such as heparin which are useful in the
treatment of diseases where excess mucus is present in the respiratory tract, such as cystic …

Particles for use in a pharmaceutical composition

JN Staniforth, DAV Morton - US Patent 8,580,306, 2013 - Google Patents
5,320,906 A* 6/1994 Eley et al.... 428/402.2 5,413,804 A* 5/1995 Rhodes.............. 426,583
5,506,203 A 4, 1996 Bäckström et all... 514/4 5,518,187 A* 5/1996 Bruno et al....... 241.5 …