Whereas the two-dimensional (2D) visualisation of biological samples is routine, three-
dimensional (3D) imaging remains a time-consuming and relatively specialised pursuit …

Scaffolds for tissue engineering application may be made from a collagenous extracellular
matrix (ECM) of connective tissues because the ECM can mimic the functions of the target …

X-ray computed tomography has become an important tool for studying the microstructures
of biological soft tissues, such as ligaments and tendons. Due to the low X-ray attenuation of …

Ascending thoracic aortic aneurysm (ATAA) has been associated with diminished
biomechanical strength and disruption in the collagen fiber microarchitecture. Additionally …

Traumatic brain injury (TBI) has become a recent focus of biomedical research with a
growing international effort targeting material characterization of brain tissue and …

A nonlinear elastic microstructural model is used to investigate the relationship between
structure and function in energy-storing and positional tendons. The model is used to fit …

Tendon's primary function is a mechanical link between muscle and bone. The hierarchical
structure of tendon and specific compositional constituents are believed to be critical for …

Soft tissues exhibit complex viscoelastic behavior, including strain-rate dependence,
hysteresis, and strain-dependent relaxation. In this paper, a model for soft tissue …

Constitutive models for soft tissue mechanics are typically constructed by fitting
phenomenological models to experimental measurements. However, a significant challenge …

We introduce a fundamental restriction on the strain energy function and stress tensor for
initially stressed elastic solids. The restriction applies to strain energy functions that are …