In this review, we compare four assays that are currently used to measure HIV integration
and discuss their strengths and weaknesses. We then outline advances that have been …

HIV-1 spreads through both the release of cell-free particles and by cell-to-cell transmission.
Mounting evidence indicates that cell-to-cell transmission is more efficient than cell-free …

Abstract Background Quiescent CD4+ T lymphocytes are highly refractory to HIV-1 infection
due to a block at reverse transcription. Results Examination of SAMHD1 expression in …

Chronic immune activation is a major complication of antiretroviral therapy (ART) for HIV
infection and can cause a devastating immune reconstitution inflammatory syndrome (IRIS) …

Resting CD4+ T lymphocytes resist human immunodeficiency virus (HIV) infection. Here, we
provide evidence that exosomes from HIV-1-infected cells render resting human primary …

Despite the effectiveness of highly active antiretroviral therapy (HAART) in treating
individuals infected with HIV, HAART is not a cure. A latent reservoir, composed mainly of …

Human immunodeficiency virus (HIV)–resistant commercial sex workers provide a unique
opportunity to study correlates of protection associated with natural resistance to HIV …

HIV-1 is transmitted between T cells through the release of cell-free particles and through
cell-cell contact. Cell-to-cell transmission is more efficient than cell-free virus transmission …

Latently infected cells form the major obstacle to HIV eradication. Studies of HIV latency
have been generally hindered by the lack of a robust and rapidly deployable cell model that …

Objective: The goal of this study was to investigate whether the location of HIV integration
differs in resting versus activated T cells, a feature that could contribute to the formation of …