Comparative effects of 18 antipsychotics on metabolic function in patients with schizophrenia, predictors of metabolic dysregulation, and association with …

T Pillinger, RA McCutcheon, L Vano, Y Mizuno… - The Lancet …, 2020 - thelancet.com
Background Antipsychotic treatment is associated with metabolic disturbance. However, the
degree to which metabolic alterations occur in treatment with different antipsychotics is …

[PDF][PDF] Treatment of patients with schizophrenia

AF Lehman, LB Dixon, TH McGlashan… - American Psychiatric …, 2010 - umh1946.umh.es
Originally published in February 2004. This guideline is more than 5 years old and has not
yet been updated to ensure that it reflects current knowledge and practice. In accordance …

Antipsychotic-induced weight gain: a comprehensive research synthesis

DB Allison, JL Mentore, M Heo… - American journal of …, 1999 - Am Psychiatric Assoc
OBJECTIVE: The purpose of this study was to estimate and compare the effects of
antipsychotics—both the newer ones and the conventional ones—on body weight …

Clozapine, diabetes mellitus, weight gain, and lipid abnormalities: a five-year naturalistic study

DC Henderson, E Cagliero, C Gray… - American Journal of …, 2000 - Am Psychiatric Assoc
OBJECTIVE: The goal of this 5-year naturalistic study of patients treated with clozapine was
to examine the incidence of treatment-emergent diabetes mellitus in relation to other factors …

Antipsychotic-induced weight gain: a review of the literature

DB Allison, DE Casey - Journal of Clinical Psychiatry, 2001 - psychiatrist.com
With the availability of the so-called novel antipsychotic agents, extrapyramidal symptoms
are becoming decreasingly problematic for patients with schizophrenia, and simultaneously …

The effects of antipsychotic therapy on serum lipids: a comprehensive review

JM Meyer, CE Koro - Schizophrenia research, 2004 - Elsevier
Objectives: The purpose of this paper is to review the literature since 1970 documenting the
effects of antipsychotic agents on serum lipids, including a discussion of possible …

Novel antipsychotics: comparison of weight gain liabilities

DA Wirshing, WC Wirshing, L Kysar… - Journal of Clinical …, 1999 - psychiatrist.com
Background: We performed a retrospective analysis of 122 clinical records of 92 male
patients with DSM-III-R schizophrenia to examine the relative weight gain liabilities of …

Clozapine's multiple cellular mechanisms: What do we know after more than fifty years? A systematic review and critical assessment of translational mechanisms …

A de Bartolomeis, L Vellucci, A Barone… - Pharmacology & …, 2022 - Elsevier
Almost fifty years after its first introduction into clinical care, clozapine remains the only
evidence-based pharmacological option for treatment-resistant schizophrenia (TRS), which …

Body weight gain induced by antipsychotic drugs: mechanisms and management

T Baptista - Acta Psychiatrica Scandinavica, 1999 - Wiley Online Library
Baptista T. Body weight gain induced by antipsychotic drugs: mechanisms and
management. Acta Psychiatrica Scand 1999: 100: 3–16.© Munksgaard 1999. Long‐term …

Childhood-onset schizophrenia: a double-blind clozapine-haloperidol comparison

S Kumra, JA Frazier, LK Jacobsen… - Archives of general …, 1996 - jamanetwork.com
Background: Childhood-onset schizophrenia is a rare but severe form of the disorder that is
often treatmentrefractory. In this study, the efficacy and adverse effects of clozapine and …