Harnessing the therapeutic potential of the stem cell secretome in neonatal diseases
S Tung, E Delavogia, A Fernandez-Gonzalez… - Seminars in …, 2023 - Elsevier
Preterm birth and intra-partum related complications account for a substantial amount of
mortality and morbidity in the neonatal period despite significant advancements in neonatal …
mortality and morbidity in the neonatal period despite significant advancements in neonatal …
Extracellular vesicles in corneal fibrosis/scarring
Communication between cells and the microenvironment is a complex, yet crucial, element
in the development and progression of varied physiological and pathological processes …
in the development and progression of varied physiological and pathological processes …
Extracellular vesicles in the cornea: Insights from other tissues
Extracellular vesicles (EVs) are phospholipid bilayer‐bound particles secreted by cells that
have been found to be important in mediating cell‐cell communication, signal transduction …
have been found to be important in mediating cell‐cell communication, signal transduction …
Antenatal mesenchymal stromal cell extracellular vesicle therapy prevents preeclamptic lung injury in mice
ES Taglauer, A Fernandez-Gonzalez… - American Journal of …, 2022 - atsjournals.org
In preeclamptic pregnancies, a variety of intrauterine alterations lead to abnormal
placentation, release of inflammatory and/or antiangiogenic factors, and subsequent fetal …
placentation, release of inflammatory and/or antiangiogenic factors, and subsequent fetal …
Extracellular vesicles secreted by corneal myofibroblasts promote corneal epithelial cell migration
Corneal epithelial wound healing is a multifaceted process that encompasses cell
proliferation, migration, and communication from the corneal stroma. Upon corneal injury …
proliferation, migration, and communication from the corneal stroma. Upon corneal injury …
Antenatal mesenchymal stromal cell extracellular vesicle treatment preserves lung development in a model of bronchopulmonary dysplasia due to chorioamnionitis
AN Abele, ES Taglauer, M Almeda… - … of Physiology-Lung …, 2022 - journals.physiology.org
Antenatal stressors such as chorioamnionitis (CA) increase the risk for bronchopulmonary
dysplasia (BPD). Studies have shown that experimental BPD can be ameliorated by …
dysplasia (BPD). Studies have shown that experimental BPD can be ameliorated by …
Moving bronchopulmonary dysplasia research from the bedside to the bench
M Gilfillan, V Bhandari - American Journal of Physiology …, 2022 - journals.physiology.org
Although advances in the respiratory management of extremely preterm infants have led to
improvements in survival, this progress has not yet extended to a reduction in the incidence …
improvements in survival, this progress has not yet extended to a reduction in the incidence …
Novel therapeutic and diagnostic approaches for preeclampsia
M Vatish, VR Powys, AS Cerdeira - Current Opinion in …, 2023 - journals.lww.com
We provide an updated framework of the current approaches to define and diagnose
preeclampsia. Disease modifying therapies (in particular, targeting the angiogenic pathway) …
preeclampsia. Disease modifying therapies (in particular, targeting the angiogenic pathway) …
[HTML][HTML] Focus: The Science of Stress: Mesenchymal Stem/Stromal Cells and Their Role in Oxidative Stress Associated with Preeclampsia
GD Kusuma, HM Georgiou, AV Perkins… - The Yale Journal of …, 2022 - ncbi.nlm.nih.gov
Preeclampsia (PE) is a serious medically important disorder of human pregnancy, which
features de novo pregnancy-induced hypertension and proteinuria. The severe form of PE …
features de novo pregnancy-induced hypertension and proteinuria. The severe form of PE …
[HTML][HTML] The pathological and therapeutic roles of mesenchymal stem cells in preeclampsia
S Jin, C Wu, M Chen, D Sun, H Zhang - Frontiers in Medicine, 2022 - frontiersin.org
MSCs have made progress in the treatment of ischemic and inflammatory diseases. PE is an
ischemic and inflammatory injury that occurs in the placenta. Our paper summarized the new …
ischemic and inflammatory injury that occurs in the placenta. Our paper summarized the new …