Clusterin (CLU) or APOJ is a multifunctional glycoprotein that has been implicated in several
physiological and pathological states, including Alzheimer's disease (AD). With a prominent …

Several lines of epidemiological evidence link increased levels of high-density lipoprotein-
cholesterol (HDL-C) with lower risk of Alzheimer's disease (AD). This observed relationship …

2014-11-12 Assigned to IMMATICS BIOTECHNOLOGIES GMBH reassignment IMMATICS
BIOTECHNOLOGIES GMBH ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT …

Several isoforms of apolipoprotein J/clusterin (CLU) are encoded from a single gene located
on chromosome 8 in humans. These isoforms are ubiquitously expressed in the tissues, and …

Clusterin (CLU) is a highly evolutionary conserved glycoprotein with multiple isoform-
specific functions and is widely distributed in different species. Accumulated evidence has …

The multifaceted protein clusterin (CLU) has been challenging researchers for more than 35
years. The characterization of CLU as a molecular chaperone was one of the major …

Expression of clusterin (CLU) closely correlates with the regulation of apoptosis in cancer.
Although endoplasmic reticulum (ER) stress-induced upregulation and retrotranslocation of …

Blue light, a high-energy radiation in the visible light spectrum, was recently reported to
induce skin pigmentation. In this study, we investigated the involvement of TRPV1-mediated …

Clusterin (CLU) is an evolutionary conserved molecular chaperone present in different
human tissues and fluids and established to be a significant cancer regulator. It controls …

Sporadic or late-onset Alzheimer's disease (AD) is expected to affect 50% of individuals
reaching 85 years of age. The most significant genetic risk factor for late-onset AD is the e4 …