Introduction: The disorder insomnia represents a relevant and frequent condition in clinical
care. Cognitive behavioral therapy of insomnia (CBT-I) is regarded as first line treatment …

Background Although originally marketed as safe alternatives to the habit-forming
benzodiazepines, growing numbers of zaleplon, zolpidem, and zopiclone (“Z-drugs”) clinical …

Background About 30% of regular cannabis users report withdrawal symptoms on cessation
of prolonged use, such as irritability, insomnia, decreased appetite, depressed mood …

Objectives Increasing evidence points to the harmful effects of long‐term benzodiazepine
treatment. Our objective was to study the incidence of, and predictors for, long‐term use of …

Our objective was to quantify the impact on the use of zolpidem of the obligation
implemented in France in 2017 to use secure prescription pads to prescribe it. We …

Background: Hypnotics have been linked to suicidal behaviors. While existing evidence has
established findings of associations, more knowledge is needed regarding benzodiazepine …

Prescription medicine misuse, especially misuse of opioids has become a major public
healthcare issue in many developed countries such as the USA and Australia where this is …

Although believed safer compared to short-acting benzodiazepines (BZD), in the past few
years a growing concern has developed relating to the abuse of Z-drugs, and specifically of …

Background. Sleep disturbances and benzodiazepine (BZD)/Z‐drug use are common in
patients with bipolar disorder (BD). Objective. To investigate the short‐and long‐term effects …

В статье анализируются клинические, эпидемиологические и фармакологические
аспекты проблемы злоупотребления психофармакологическими лекарственными …