Metformin is the first-line drug treatment for type 2 diabetes. Globally, over 100 million
patients are prescribed this drug annually. Metformin was discovered before the era of target …

Copper (Cu), a redox active metal, is an essential nutrient for all species studied to date.
During the past decade, there has been increasing interest in the concept that marginal …

It is well known that oxidation caused by reactive oxygen species (ROS) is a major cause of
cellular damage and death and has been implicated in cancer, neurodegenerative, and …

Copper is an essential trace metal element that significantly affects human physiology and
pathology by regulating various important biological processes, including mitochondrial …

The prevalence of Type 2 Diabetes Mellitus (T2DM) is internationally ever-growing.
Therefore, prevention, diagnostics, and control of insulin resistance and T2DM are of …

Copper is an essential trace metal element that significantly affects human physiology and
pathology by regulating various important biological processes, including mitochondrial …

BACKGROUND: Impaired zinc metabolism is prominent in chronic disorders including
cardiovascular disease and diabetes. Zinc has the potential to affect glucose homeostasis in …

Background Heavy metals may play an important role as environmental risk factors in
diabetes mellitus. This study aimed to explore the association of HbA1c with As, Cd, Cu, Ni …

High blood copper (Cu) and homocysteine (Hcy) concentrations have been independently
reported as risk factors for cardiovascular diseases. When they are simultaneously …

Diabetes Mellitus (DM) is characterized by elevated blood glucose levels (hyperglycemia). It
can occur due to impaired secretion or action of the hormone insulin, which is produced by …