The role of epidermal growth factor receptor family of receptor tyrosine kinases in mediating diabetes-induced cardiovascular complications
Diabetes mellitus is a major debilitating disease whose global incidence is progressively
increasing with currently over 463 million adult sufferers and this figure will likely reach over …
increasing with currently over 463 million adult sufferers and this figure will likely reach over …
Emerging role of Unfolded Protein Response (UPR) mediated proteotoxic apoptosis in diabetes
Endoplasmic reticulum (ER) is a crucial single membrane organelle that acts as a quality
control system for cellular proteins as it is intricately involved in their synthesis, folding and …
control system for cellular proteins as it is intricately involved in their synthesis, folding and …
Exploring the mechanisms underlying the therapeutic effect of Salvia miltiorrhiza in diabetic nephropathy using network pharmacology and molecular docking
L Zhang, L Han, X Wang, Y Wei, J Zheng… - Bioscience …, 2021 - portlandpress.com
The mechanisms underlying the therapeutic effect of Salvia miltiorrhiza (SM) on diabetic
nephropathy (DN) were examined using a systematic network pharmacology approach and …
nephropathy (DN) were examined using a systematic network pharmacology approach and …
BM-MSCs alleviate diabetic nephropathy in male rats by regulating ER stress, oxidative stress, inflammation, and apoptotic pathways
T Khamis, A Abdelkhalek, H Abdellatif… - Frontiers in …, 2023 - frontiersin.org
Introduction: Diabetic nephropathy (DN), a chronic kidney disease, is a major cause of end-
stage kidney disease worldwide. Mesenchymal stem cells (MSCs) have become a …
stage kidney disease worldwide. Mesenchymal stem cells (MSCs) have become a …
Based on network pharmacology tools to investigate the molecular mechanism of Cordyceps sinensis on the treatment of diabetic nephropathy
Background. Diabetic nephropathy (DN) is one of the most common complications of
diabetes mellitus and is a major cause of end‐stage kidney disease. Cordyceps sinensis …
diabetes mellitus and is a major cause of end‐stage kidney disease. Cordyceps sinensis …
The Role of Oxidative Stress in Tumorigenesis and Progression
K Li, Z Deng, C Lei, X Ding, J Li, C Wang - Cells, 2024 - mdpi.com
Oxidative stress refers to the imbalance between the production of reactive oxygen species
(ROS) and the endogenous antioxidant defense system. Its involvement in cell senescence …
(ROS) and the endogenous antioxidant defense system. Its involvement in cell senescence …
MicroRNAs in the progress of diabetic nephropathy: A systematic review and meta‐analysis
L Wang, Y Gao, B Song, G Yu, H Chen… - Evidence‐Based …, 2019 - Wiley Online Library
Background. We conducted a systematic review and meta‐analysis of existing literature to
evaluate the different outcomes of microRNAs (miRNAs) in diabetic nephropathy (DN) …
evaluate the different outcomes of microRNAs (miRNAs) in diabetic nephropathy (DN) …
Connexin32 plays a crucial role in ROS-mediated endoplasmic reticulum stress apoptosis signaling pathway in ischemia reperfusion-induced acute kidney injury
Y Gu, F Huang, Y Wang, C Chen, S Wu, S Zhou… - Journal of translational …, 2018 - Springer
Abstract Background Ischemia–reperfusion (I/R)-induced acute kidney injury (AKI) not only
prolongs the length of hospital stay, but also seriously affects the patient's survival rate …
prolongs the length of hospital stay, but also seriously affects the patient's survival rate …
Cell surface expression of 78-kDa glucose-regulated protein (GRP78) mediates diabetic nephropathy
R Van Krieken, N Mehta, T Wang, M Zheng, R Li… - Journal of Biological …, 2019 - ASBMB
The 78-kDa glucose-regulated protein (GRP78) is a well-established endoplasmic reticulum
(ER)-resident chaperone that maintains protein homeostasis and regulates the unfolded …
(ER)-resident chaperone that maintains protein homeostasis and regulates the unfolded …
A soy-based probiotic drink modulates the microbiota and reduces body weight gain in diet-induced obese mice
J de Carvalho Marchesin, LS Celiberto… - Journal of functional …, 2018 - Elsevier
This work investigates the effect of a soy-based probiotic drink (Enterococcus faecium CRL
183 and Bifidobacterium longum ATCC 15707) on the fecal microbiota composition, body …
183 and Bifidobacterium longum ATCC 15707) on the fecal microbiota composition, body …