COVID‐19 drug repurposing: a review of computational screening methods, clinical trials, and protein interaction assays

X Wang, Y Guan - Medicinal research reviews, 2021 - Wiley Online Library
The situation of coronavirus disease 2019 (COVID‐19) pandemic is rapidly evolving, and
medical researchers around the globe are dedicated to finding cures for the disease. Drug …

Peptides for vaccine development

IW Hamley - ACS Applied Bio Materials, 2022 - ACS Publications
This review discusses peptide epitopes used as antigens in the development of vaccines in
clinical trials as well as future vaccine candidates. It covers peptides used in potential …

Contriving multi-epitope subunit of vaccine for COVID-19: immunoinformatics approaches

R Dong, Z Chu, F Yu, Y Zha - Frontiers in immunology, 2020 - frontiersin.org
COVID-19 has recently become the most serious threat to public health, and its prevalence
has been increasing at an alarming rate. The incubation period for the virus is~ 1–14 days …

In silico analysis of epitope-based vaccine candidate against tuberculosis using reverse vaccinology

S Bibi, I Ullah, B Zhu, M Adnan, R Liaqat, WB Kong… - Scientific reports, 2021 - nature.com
Tuberculosis (TB) kills more individuals in the world than any other disease, and a threat
made direr by the coverage of drug-resistant strains of Mycobacterium tuberculosis (Mtb) …

Exploring the out of sight antigens of SARS-CoV-2 to design a candidate multi-epitope vaccine by utilizing immunoinformatics approaches

A Safavi, A Kefayat, E Mahdevar, A Abiri… - Vaccine, 2020 - Elsevier
SARS-CoV-2 causes a severe respiratory disease called COVID-19. Currently, global health
is facing its devastating outbreak. However, there is no vaccine available against this virus …

Screening of phytochemical compounds of Tinospora cordifolia for their inhibitory activity on SARS-CoV-2: an in silico study

S Krupanidhi, K Abraham Peele… - Journal of …, 2021 - Taylor & Francis
In the present study, we explored phytochemical constituents of Tinospora cordifolia in terms
of its binding affinity targeting the active site pocket of the main protease (3CL pro) of SARS …

Virtual screening-driven drug discovery of SARS-CoV2 enzyme inhibitors targeting viral attachment, replication, post-translational modification and host immunity …

MTJ Quimque, KIR Notarte… - Journal of …, 2021 - Taylor & Francis
The novel coronavirus SARS-CoV2, the causative agent of the pandemic disease COVID-
19, emerged in December 2019 forcing lockdown of communities in many countries. The …

Design of a multi-epitope vaccine against SARS-CoV-2 using immunoinformatics approach

S Sanami, M Zandi, B Pourhossein, GR Mobini… - International journal of …, 2020 - Elsevier
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) caused COVID-19 disease
in China. So far, no vaccine has licensed to protect against infection with COVID-19 …

Design of a multi-epitope-based vaccine targeting M-protein of SARS-CoV2: an immunoinformatics approach

VS Ayyagari, V TC, AP K, K Srirama - Journal of biomolecular …, 2022 - Taylor & Francis
In the present study, one of the targets present on the envelopes of coronaviruses,
membrane glycoprotein (M) was chosen for the design of a multi-epitope vaccine by …

Chemical-informatics approach to COVID-19 drug discovery: Monte Carlo based QSAR, virtual screening and molecular docking study of some in-house molecules …

SA Amin, K Ghosh, S Gayen, T Jha - Journal of Biomolecular …, 2021 - Taylor & Francis
Abstract World Health Organization characterized novel coronavirus disease (COVID-19),
caused by severe acute respiratory syndrome (SARS) coronavirus-2 (SARS-CoV-2) as …