The global prevalence of obesity has more than doubled over the past four decades,
currently affecting more than a billion individuals. Beyond its recognition as a high-risk …

The heterocellular nature of the heart has been receiving increasing attention in recent
years. In addition to cardiomyocytes as the prototypical cell type of the heart, non-myocytes …

Background Semaglutide, a glucagon-like peptide-1 receptor agonist, has been shown to
reduce the risk of adverse cardiovascular events in patients with diabetes. Whether …

Background Adipose tissue-derived adipokines are involved in various crosstalk between
adipose tissue and other organs. Omentin1, a novel adipokine, exerts vital roles in the …

Obesity is a modifiable cardiovascular risk factor, but adipose tissue (AT) depots in humans
are anatomically, histologically, and functionally heterogeneous. For example, visceral AT is …

Overweight and obesity are characterized by excessive fat mass accumulation produced
when energy intake exceeds energy expenditure. One plausible way to control energy …

Adipose tissue is a critical regulator of systemic metabolism and bodily homeostasis as it
secretes a myriad of adipokines, including inflammatory and anti-inflammatory cytokines. As …

Abstract Objective Sodium-glucose cotransporter-2 (SGLT-2) inhibitors therapies were
reported to affect adipose tissue distribution. However, the available evidence about the …

Aims The concept of “atrial cardiomyopathy”(AtCM) had been percolating through the
literature since its first mention in 1972. Since then, publications using the term were …

Aims Human epicardial adipose tissue (EAT) plays a crucial role in the development and
progression of coronary artery disease, atrial fibrillation, and heart failure. Microscopically …