Congenital heart disease is the most common birth defect, and because of major advances
in medical and surgical management, there are now more adults living with congenital heart …

Congenital heart disease (CHD) is the most common congenital anomaly in newborn
babies. Cardiac malformations have been produced in multiple experimental animal …

Although cardiac abnormalities have been observed in a growing class of human disorders
caused by defective primary cilia, the function of cilia in the heart remains an underexplored …

Congenital heart disease (CHD) affects nearly 1% of the population. It is a complex disease,
which may be caused by multiple genetic and environmental factors. Studies in human …

Genetic disorders account for a wide range of renal diseases emerging during childhood
and adolescence. Due to the utilization of modern biochemical and biomedical techniques …

Primary cilia are unique sensory organelles that coordinate a wide variety of different
signaling pathways to control cellular processes during development and in tissue …

Humans and other vertebrates exhibit left–right (LR) asymmetric arrangement of the internal
organs, and failure to establish normal LR asymmetry leads to internal laterality disorders …

Primary cilia are microtubule-based organelles found in most mammalian cell types. Cilia
act as sensory organelles that transmit extracellular clues into intracellular signals for …

Although congenital heart disease (CHD) is the most common survivable birth defect, the
etiology of most CHD remains unclear. Several lines of evidence from humans and …

Leber congenital amaurosis (LCA) and early‐onset retinal dystrophy (EORD) are severe
inherited retinal dystrophy that can cause deep blindness childhood. They represent 5% of …