Insulin-like growth factors binding protein-6 (IGFBP-6) is involved in a relevant number of
cellular activities and represents an important factor in the immune response, particularly in …

Asthma is a complex disease with striking disparities across racial and ethnic groups.
Despite its relatively high burden, representation of individuals of African ancestry in asthma …

Mesenchymal stem cells (MSCs) have been reported as promising candidates for the
treatment of various diseases, especially allergic diseases, as they have the capacity to …

Human siglecs are a family of 14 sialic acid-binding proteins, most of which are expressed
on subsets of immune cells where they regulate immune responses. Siglec-8 is expressed …

Viral vectors have been applied successfully to generate disease-related animal models
and to functionally characterize target genes in vivo. However, broader application is still …

Background. Although mesenchymal stem cell‐(MSC‐) derived extracellular vesicles (EVs)
are as effective as MSCs in the suppression of allergic airway inflammation, few studies …

Cystic Fibrosis (CF) patients are prone to contracting bacterial lung infections with
opportunistic pathogens, especially Pseudomonas aeruginosa. Prolonged P. aeruginosa …

The lung is an accomplished organ for gas exchanges and directly faces the external
environment, consequently exposing its large epithelial surface. It is also the putative …

The nanosized vesicles secreted from various cell types into the surrounding extracellular
space are called extracellular vesicles (EVs). Although mesenchymal stem cell-derived EVs …

Glioblastoma (GBM) is the most common primary malignant brain tumor in adults. The
insulin‐like growth factor‐binding protein (IGFBP) family is involved in tumorigenesis and …