Anhedonia is a core symptom of depression and of several psychiatric disorders. Anhedonia
has however expanded from its original definition to encompass a spectrum of reward …

Objective: Treatment of different depression symptoms may require different brain
stimulation targets with different underlying brain circuits. The authors sought to identify such …

The recognition of emotions in facial expressions (REFE) is a core construct of social
cognition. In the last decades, studies have showed that REFE is altered in major depressive …

Background Anhedonia is one of the defining features of depression but it remains difficult to
target and treat. Transcranial magnetic stimulation (TMS) is a proven treatment for …

Background Anhedonia and rumination are mental disorders' transdiagnostic features but
remain difficult to treat. Transcranial direct current stimulation (tDCS) is a proven treatment …

Background Two prominent risk factors for major depressive disorder (MDD) are childhood
maltreatment (CM) and familial risk for MDD. Despite having these risk factors, there are …

Background There are currently no effective treatments specifically targeting anticipatory
anhedonia, a major symptom of severe depression which is associated with poor outcomes …

Aim Vascular endothelial growth factor (VEGF) has been implicated in mediating the effect of
antidepressant therapies as it plays a significant role in the neurogenesis. Anhedonia, an …

Anhedonia is the loss of pleasure or motivation to engage in previously enjoyable activities,
and is a transdiagnostic symptom associated with significant clinical impairment. Anhedonia …

Purpose Deficits in facial emotional intensity recognition have been associated with social
cognition in patients with major depression. The study examined multiple event-related …