[HTML][HTML] Metabolism disrupting chemicals and metabolic disorders

JJ Heindel, B Blumberg, M Cave, R Machtinger… - Reproductive …, 2017 - Elsevier
The recent epidemics of metabolic diseases, obesity, type 2 diabetes (T2D), liver lipid
disorders and metabolic syndrome have largely been attributed to genetic background and …

Child health, developmental plasticity, and epigenetic programming

Z Hochberg, R Feil, M Constancia, M Fraga… - Endocrine …, 2011 - academic.oup.com
Plasticity in developmental programming has evolved in order to provide the best chances of
survival and reproductive success to the organism under changing environments …

The estrogenic endocrine disrupting chemical bisphenol A (BPA) and obesity

FS Vom Saal, SC Nagel, BL Coe, BM Angle… - Molecular and cellular …, 2012 - Elsevier
There is increasing experimental and epidemiological evidence that fetal programming of
genetic systems is a contributing factor in the recent increase in adult obesity and other …

Metabolic disruption in male mice due to fetal exposure to low but not high doses of bisphenol A (BPA): evidence for effects on body weight, food intake, adipocytes …

BM Angle, RP Do, D Ponzi, RW Stahlhut, BE Drury… - Reproductive …, 2013 - Elsevier
Exposure to bisphenol A (BPA) is implicated in many aspects of metabolic disease in
humans and experimental animals. We fed pregnant CD-1 mice BPA at doses ranging from …

Soy, phytoestrogens and metabolism: A review

CR Cederroth, S Nef - Molecular and cellular endocrinology, 2009 - Elsevier
Of any plant, soy contains the largest concentration of isoflavones, a class of
phytoestrogens. Phytoestrogens are structurally similar to estradiol and mimic its effects. Soy …

Mouse models of diabetic neuropathy

PD O'Brien, SA Sakowski, EL Feldman - ILAR journal, 2014 - academic.oup.com
Diabetic peripheral neuropathy (DPN) is the most common complication of diabetes and is
associated with significant morbidity and mortality. DPN is characterized by progressive …

Phytochemicals in regulating fatty acid β-oxidation: Potential underlying mechanisms and their involvement in obesity and weight loss

HPV Rupasinghe, S Sekhon-Loodu, T Mantso… - Pharmacology & …, 2016 - Elsevier
Excessive accumulation of fat as the result of more energy intake and less energy
expenditure is known as obesity. Lipids are essential components in the human body and …

Bisphenol A: perinatal exposure and body weight

BS Rubin, AM Soto - Molecular and cellular endocrinology, 2009 - Elsevier
Bisphenol A (BPA) is a component of polycarbonate and other plastics including resins that
line food and beverage containers. BPA is known to leach from products in contact with food …

Investigation of relationships between urinary biomarkers of phytoestrogens, phthalates, and phenols and pubertal stages in girls

MS Wolff, SL Teitelbaum, SM Pinney… - Environmental …, 2010 - ehp.niehs.nih.gov
Background Hormonally active environmental agents may alter the course of pubertal
development in girls, which is controlled by steroids and gonadotropins. Objectives We …

Short-term treatment with bisphenol-A leads to metabolic abnormalities in adult male mice

TM Batista, P Alonso-Magdalena, E Vieira… - PloS one, 2012 - journals.plos.org
Bisphenol-A (BPA) is one of the most widespread endocrine disrupting chemicals (EDC)
used as the base compound in the manufacture of polycarbonate plastics. Although …