Cardiovascular disease (CVD) is a serious health challenge, causing more deaths
worldwide than cancer. The vascular endothelium, which forms the inner lining of blood …

Mechanical forces influence homeostasis in virtually every tissue [1, 2]. Tendon, constantly
exposed to variable mechanical force, is an excellent model in which to study the conversion …

Bottom-up engineering of microscale tissue (" microtissue") constructs to recapitulate
partially the complex structure–function relationships of liver parenchyma has been realized …

Living systems face a fundamental challenge of orchestrating exchange of nutrients and
oxygen throughout 3D space in order to satisfy their metabolic needs.[1] In nature, vascular …

There is no technology available to support failing lung function for patients outside the
hospital. An implantable lung assist device would augment lung function as a bridge to …

Branched vascular networks are a central component of scaffold architecture for solid organ
tissue engineering. In this work, seven biomimetic principles were established as the major …

Tendons are frequently injured and have limited regenerative capacity. This motivates tissue
engineering efforts aimed at restoring tendon function through strategies to direct functional …

Microfluidic systems provide many advantages for live cell imaging, including improved cell
culture micro-environments, control of flows and dynamic exposure profiles, and …

Unlike a conventional aircraft's wing, a morphing aircraft's wing could undergo large
deformations in order to fly efficiently. This requires a wing's skin meeting conflicting …

In this paper, we present the computational fluid dynamics (CFD) simulations of bubble
transport in a first generation bifurcating microchannel. In the present study, the human …