Molecular strategies for the utilisation of human milk oligosaccharides by infant gut-associated bacteria
LJ Kiely, K Busca, JA Lane… - FEMS Microbiology …, 2023 - academic.oup.com
A number of bacterial species are found in high abundance in the faeces of healthy breast-
fed infants, an occurrence that is understood to be, at least in part, due to the ability of these …
fed infants, an occurrence that is understood to be, at least in part, due to the ability of these …
Structure and function of microbial α-l-fucosidases: a mini review
Fucose is a monosaccharide commonly found in mammalian, insect, microbial and plant
glycans. The removal of terminal α-l-fucosyl residues from oligosaccharides and …
glycans. The removal of terminal α-l-fucosyl residues from oligosaccharides and …
Linking human milk oligosaccharide metabolism and early life gut microbiota: Bifidobacteria and beyond
C Lordan, AK Roche, D Delsing, A Nauta… - Microbiology and …, 2024 - Am Soc Microbiol
Human milk oligosaccharides (HMOs) are complex, multi-functional glycans present in
human breast milk. They represent an intricate mix of heterogeneous structures which reach …
human breast milk. They represent an intricate mix of heterogeneous structures which reach …
CRISPR-Cas-based identification of a sialylated human milk oligosaccharides utilization cluster in the infant gut commensal Bacteroides dorei
S Kijner, D Ennis, S Shmorak, A Florentin… - Nature …, 2024 - nature.com
The infant gut microbiome is impacted by early-life feeding, as human milk oligosaccharides
(HMOs) found in breastmilk cannot be digested by infants and serve as nutrients for their gut …
(HMOs) found in breastmilk cannot be digested by infants and serve as nutrients for their gut …
Milk oligosaccharide-driven persistence of Bifidobacterium pseudocatenulatum modulates local and systemic microbial metabolites upon synbiotic treatment in …
Background Bifidobacteria represent an important gut commensal in humans, particularly
during initial microbiome assembly in the first year of life. Enrichment of Bifidobacterium is …
during initial microbiome assembly in the first year of life. Enrichment of Bifidobacterium is …
Early development of infant gut microbiota in relation to breastfeeding and human milk oligosaccharides
Background Infant gut microbiota composition is influenced by various factors early in life.
Here, we investigate associations between infant gut microbiome development, infant age …
Here, we investigate associations between infant gut microbiome development, infant age …
2′-Fucosyllactose Increases the Abundance of Blautia in the Presence of Extracellular Fucosidase-Possessing Bacteria
A Horigome, N Hashikura, K Yoshida, J Xiao… - Frontiers in …, 2022 - frontiersin.org
Blautia is a genus of anaerobic bacteria that is widely distributed in the mammalian gut.
Recently, an increasing body of research has demonstrated a link between this genus and …
Recently, an increasing body of research has demonstrated a link between this genus and …
Recent progress in fucosylated derivatives of lacto-N-tetraose and lacto-N-neotetraose
Human milk oligosaccharides (HMOs) have attracted considerable attention owing to their
unique physiological functions. Two important tetrasaccharides, lacto-N-tetraose (LNT) and …
unique physiological functions. Two important tetrasaccharides, lacto-N-tetraose (LNT) and …
Human milk oligosaccharide utilization in intestinal Bifidobacteria is governed by global transcriptional regulator NagR
Bifidobacterium longum subsp. infantis is a prevalent beneficial bacterium that colonizes the
human neonatal gut and is uniquely adapted to efficiently use human milk oligosaccharides …
human neonatal gut and is uniquely adapted to efficiently use human milk oligosaccharides …
Engineered plants provide a photosynthetic platform for the production of diverse human milk oligosaccharides
Human milk oligosaccharides (HMOs) are a diverse class of carbohydrates which support
the health and development of infants. The vast health benefits of HMOs have made them a …
the health and development of infants. The vast health benefits of HMOs have made them a …