Relationship between periodontitis and rheumatoid arthritis: review of the literature

VMA Araújo, IM Melo, V Lima - Mediators of inflammation, 2015 - Wiley Online Library
Periodontitis (PD) and rheumatoid arthritis (RA) are immunoinflammatory diseases where
leukocyte infiltration and inflammatory mediators induce alveolar bone loss, synovitis, and …

A systematic review and meta-analysis on multiple cytokine gene polymorphisms in the pathogenesis of periodontitis

X Liu, H Li - Frontiers in immunology, 2022 - frontiersin.org
Aim Periodontitis is an inflammatory disease that destroys both soft and hard periodontal
tissues. However, a complex periodontal cytokine network remains unclear. This systematic …

Identification of the different salivary Interleukin-6 profiles in patients with periodontitis: a cross-sectional study

G Isola, AL Giudice, A Polizzi, A Alibrandi… - Archives of Oral …, 2021 - Elsevier
Objective The aim of this study was to analyze and identify the association among salivary
interleukin-6 (IL-6) levels and periodontitis (PT) and to determine the significant trend of this …

Immunomodulatory factors gene polymorphisms in chronic periodontitis: an overview

Z Heidari, B Moudi, H Mahmoudzadeh-Sagheb - BMC Oral Health, 2019 - Springer
Background Chronic periodontitis (CP), defines as destruction of the supporting tissues of
the teeth and resorption of the alveolar bone. It is widespread in human populations and …

The role of interleukin 6 in periodontitis and its complications

M Mazurek-Mochol, T Bonsmann, M Mochol… - International Journal of …, 2024 - mdpi.com
Interleukin 6 (IL-6) is a pleomorphic pro-inflammatory cytokine that is strongly associated
with local as well as systemic inflammatory processes. Its role in physiological and …

Cytokines and their genetic polymorphisms related to periodontal disease

M Kozak, E Dabrowska-Zamojcin… - Journal of clinical …, 2020 - mdpi.com
Periodontal disease (PD) is a chronic inflammatory disease caused by the accumulation of
bacterial plaque biofilm on the teeth and the host immune responses. PD pathogenesis is …

[HTML][HTML] Macrophage M1 polarization mediated via the IL-6/STAT3 pathway contributes to apical periodontitis induced by Porphyromonas gingivalis

X Chen, J Dou, Z Fu, Y Qiu, L Zou, D Huang… - Journal of Applied Oral …, 2022 - SciELO Brasil
Objective: To investigate the involvement of IL-6/STAT3 signaling pathway activation in
macrophage polarization and bone destruction related to apical periodontitis (AP) stimulated …

[HTML][HTML] Human β-defensin 3 inhibits periodontitis development by suppressing inflammatory responses in macrophages

D Cui, J Lyu, H Li, L Lei, T Bian, L Li, F Yan - Molecular Immunology, 2017 - Elsevier
Abstract Human β-defensin 3 (hBD3) is a cationic peptide with immunomodulatory effects on
both innate and acquired immune responses. Periodontitis, an inflammatory disease that …

Interleukin‐6‐174G/C polymorphism contributes to periodontitis susceptibility: an updated meta‐analysis of 21 case‐control studies

J Zhu, B Guo, M Fu, W Guo, Y Yuan, H Yuan… - Disease …, 2016 - Wiley Online Library
Introduction. Chronic Periodontitis (CP) is suggested to be related to gene variations.
Present study aims to quantitatively estimate the association between interleukin‐6‐(IL‐6‐) …

The association between periodontitis and interleukin-6 genetic polymorphism-174 G/C: A meta-analysis

B Zhao, R Li - Archives of oral biology, 2018 - Elsevier
Background To evaluate the association between periodontitis and interleukin-6 (IL6)-174
G/C polymorphism by data synthesis and subgroup analysis. Methods Eighteen case-control …