Using microemulsions: formulation based on knowledge of their mesostructure

M Gradzielski, M Duvail, PM de Molina… - Chemical …, 2021 - ACS Publications
Microemulsions, as thermodynamically stable mixtures of oil, water, and surfactant, are
known and have been studied for more than 70 years. However, even today there are still …

Recent trends of self-emulsifying drug delivery system for enhancing the oral bioavailability of poorly water-soluble drugs

P Tran, JS Park - Journal of Pharmaceutical Investigation, 2021 - Springer
Background The oral route is the most popular route for the clinical administration of drugs to
treat various diseases. Before a drug is absorbed into the blood circulation, it must undergo …

[HTML][HTML] Niosomes: a strategy toward prevention of clinically significant drug incompatibilities

HB Mohamed, SM El-Shanawany, MA Hamad… - Scientific reports, 2017 - nature.com
Drug incompatibilities are considered as one of the most critical problems in intensive care
units. In the current study, the ability of nanomaterials to prevent drug incompatibilities in …

Design and evaluation of combined atorvastatin and ezetimibe optimized self-nano emulsifying drug delivery system

AR Gardouh, AM Nasef, Y Mostafa, S Gad - Journal of Drug Delivery …, 2020 - Elsevier
The purpose was to develop, optimize and assess Self-nanoemulsifying drug delivery
system (SNEDDS) to enhance solubility and dissolution rate of the poorly-water soluble …

A combination of complexation and self-nanoemulsifying drug delivery system for enhancing oral bioavailability and anticancer efficacy of curcumin

M Shukla, S Jaiswal, A Sharma… - Drug development …, 2017 - Taylor & Francis
Objective: Curcumin, the golden spice from Indian saffron, has shown chemoprotective
action against many types of cancer including breast cancer. However, poor oral …

Self-emulsifying drug delivery systems and their marketed products: a review

GV Betageri - Asian Journal of Pharmaceutics (AJP), 2019 - asiapharmaceutics.info
Self-emulsifying drug delivery systems (SEDDS) are one of the proven methods to increase
solubility and bioavailability of poorly soluble drugs. SEDDS are isotropic mixtures …

Solid self-nanoemulsifying systems of olmesartan medoxomil: Formulation development, micromeritic characterization, in vitro and in vivo evaluation

S Beg, OP Katare, S Saini, B Garg, RK Khurana… - Powder technology, 2016 - Elsevier
The current studies entail development and evaluation of solid self-nanoemulsifying drug
delivery systems (S-SNEDDS) employing porous carriers for enhancing the oral …

Bioavailability enhanced clopidogrel-loaded solid SNEDDS: development and in-vitro/in-vivo characterization

E Abd-Elhakeem, MHM Teaima, GA Abdelbary… - Journal of Drug Delivery …, 2019 - Elsevier
The purpose of this study is to develop solid self-nanoemulsifying drug delivery systems (S-
SNEDDS) for oral bioavailability enhancement of Clopidogrel (CLP). CLP is an anti-platelet …

[HTML][HTML] A solid ultra fine self-nanoemulsifying drug delivery system (S-SNEDDS) of deferasirox for improved solubility: optimization, characterization, and in vitro …

A Alghananim, Y Özalp, B Mesut, N Serakinci, Y Özsoy… - Pharmaceuticals, 2020 - mdpi.com
The research work was designed to develop a solid self-nanoemulsifying drug delivery
system (S-SNEDDS) of deferasirox (DFX). According to the solubility studies of DFX in …

Strategic approach to developing a self-microemulsifying drug delivery system to enhance antiplatelet activity and bioavailability of ticagrelor

YG Na, JJ Byeon, M Wang, HW Huh… - International journal …, 2019 - Taylor & Francis
Background Ticagrelor (TCG) is used to inhibit platelet aggregation in patients with acute
coronary syndrome, but its poor solubility and low bioavailability limit its in vivo efficacy. The …