Review of rodent euthanasia methods

NH Shomer, KH Allen-Worthington… - Journal of the …, 2020 - ingentaconnect.com
The optimal choice of euthanasia method for laboratory rodents depends on a number of
factors, including the scientific goals of the study, the need to minimize animal pain and/or …

A review of methods used to kill laboratory rodents: issues and opportunities

JM Clarkson, JE Martin… - Laboratory …, 2022 - journals.sagepub.com
Rodents are the most widely used species for scientific purposes. A critical pre-requisite of
their use, based on utilitarian ethical reasoning, is the provision of a humane death when …

Euthanasia of laboratory mice: Are isoflurane and sevoflurane real alternatives to carbon dioxide?

N Marquardt, M Feja, H Hünigen, J Plendl, L Menken… - PLoS one, 2018 - journals.plos.org
In the European Union (EU) millions of laboratory mice are used and killed for experimental
and other scientific purposes each year. Although controversially discussed, the use of …

A good death? Report of the second Newcastle meeting on laboratory animal euthanasia

P Hawkins, MJ Prescott, L Carbone, N Dennison… - 2016 - mdpi.com
Simple Summary Millions of laboratory animals are killed each year worldwide. However,
there is a lack of consensus regarding what methods of killing are humane for many species …

A comparison of various methods of blood sampling in mice and rats: Effects on animal welfare

VS Harikrishnan, AK Hansen… - Laboratory …, 2018 - journals.sagepub.com
This study was conducted to investigate the effects of blood sampling on animal welfare in a
total of 60 NTac: SD rats and 72 C57BL/6NTac mice of both sexes. Blood was sampled …

Welfare impact of carbon dioxide euthanasia on laboratory mice and rats: a systematic review

PV Turner, DL Hickman, J Van Luijk… - Frontiers in Veterinary …, 2020 - frontiersin.org
Background: There has been increased concern about the suitability of CO2 as a method for
euthanasia of laboratory mice and rats, including the potential discomfort, pain or distress …

Systematic review: anesthetic protocols and management as confounders in rodent blood oxygen level dependent functional magnetic resonance imaging (BOLD …

AR Steiner, F Rousseau-Blass, A Schroeter… - Animals, 2021 - mdpi.com
Simple Summary To understand brain function in rats and mice functional magnetic
resonance imaging of the brain is used. With this type of “brain scan” regional changes in …

Humanely ending the life of animals: Research priorities to identify alternatives to carbon dioxide

AR Steiner, S Axiak Flammer, NJ Beausoleil, C Berg… - Animals, 2019 - mdpi.com
Simple Summary Carbon dioxide is commonly used for stunning animals prior to killing. It
allows several animals to be killed at once, reduces the need for handling, and is a reliable …

Under or absent reporting of light stimuli in testing of anxiety-like behaviors in rodents: the need for standardization

LS Neuwirth, MT Verrengia… - Frontiers in molecular …, 2022 - frontiersin.org
Behavioral neuroscience tests such as the Light/Dark Test, the Open Field Test, the Elevated
Plus Maze Test, and the Three Chamber Social Interaction Test have become both essential …

Euthanasia using gaseous agents in laboratory rodents

AM Valentim, SR Guedes, AM Pereira… - Laboratory …, 2016 - journals.sagepub.com
Several questions have been raised in recent years about the euthanasia of laboratory
rodents. Euthanasia using inhaled agents is considered to be a suitable aesthetic method …