Routes of drug administration and the corresponding physicochemical characteristics of a
given route play significant roles in therapeutic efficacy and short term/long term biological …

Type 1 diabetes therapies that afford tighter glycemic control in a more manageable and
painless manner for patients has remained a central focus of next-generation diabetes …

Three-dimensional (3D) printing, known as the most promising approach for bioartificial
organ manufacturing, has provided unprecedented versatility in delivering multi-functional …

In the last two decades, microfluidics has emerged as a powerful tool of high precision and
versatility, mainly applied to biomedicine. As a result of its strengths, the literature …

Conventional stem cell delivery typically utilize administration of directly injection of
allogenic cells or domesticated autogenic cells. It may lead to immune clearance of these …

Hydrogel microcapsules provide miniaturized and biocompatible niches for three-
dimensional (3D) in vitro cell culture. They can be easily generated by droplet-based …

A three-dimensional (3D) tissue model has significant advantages over the conventional two-
dimensional (2D) model. A 3D model mimics the relevant in-vivo physiological conditions …

Cryopreservation has utility in clinical and scientific research but implementation is highly
complex and includes labor-intensive cell-specific protocols for the addition/removal of …

Microencapsulation of living cells is a field that has been heavily investigated by many
researchers over the past two decades. Numerous experimental setups have been …

In this article, we will review the changes that have occurred in islet transplantation at the
birth of Pancreas 30 years ago. The first attempts at β-cell replacement in humans, pancreas …