Advances in biomaterial‐based spinal cord injury repair

H Shen, C Fan, Z You, Z Xiao… - Advanced Functional …, 2022 - Wiley Online Library
Spinal cord injury (SCI) often leads to the loss of motor and sensory functions and is a major
challenge in neurological clinical practice. Understanding the pathophysiological changes …

Electrical stimulation for the treatment of spinal cord injuries: A review of the cellular and molecular mechanisms that drive functional improvements

RM Dorrian, CF Berryman, A Lauto… - Frontiers in Cellular …, 2023 - frontiersin.org
Spinal cord injury (SCI) is a devastating condition that causes severe loss of motor, sensory
and autonomic functions. Additionally, many individuals experience chronic neuropathic …

An injectable rapid‐adhesion and anti‐swelling adhesive hydrogel for hemostasis and wound sealing

S Bian, L Hao, X Qiu, J Wu, H Chang… - Advanced Functional …, 2022 - Wiley Online Library
Injectable hydrogel adhesives integrating both rapid adhesion to wet tissues and anti‐
swelling in humid environments are highly desired for fast hemostasis and wound sealing in …

Comparative neuroanatomy of the lumbosacral spinal cord of the rat, cat, pig, monkey, and human

A Toossi, B Bergin, M Marefatallah, B Parhizi… - Scientific Reports, 2021 - nature.com
The overall goal of this work was to create a high-resolution MRI atlas of the lumbosacral
enlargement of the spinal cord of the rat (Sprague–Dawley), cat, domestic pig, rhesus …

Effects of polyphenols on oxidative stress, inflammation, and interconnected pathways during spinal cord injury

S Fakhri, F Abbaszadeh, SZ Moradi… - Oxidative medicine …, 2022 - Wiley Online Library
Despite the progression in targeting the complex pathophysiological mechanisms of
neurodegenerative diseases (NDDs) and spinal cord injury (SCI), there is a lack of effective …

A new framework for investigating the biological basis of degenerative cervical myelopathy [AO Spine RECODE-DCM Research Priority Number 5]: mechanical stress …

BM Davies, O Mowforth, AA Gharooni… - Global Spine …, 2022 - journals.sagepub.com
Study Design Literature Review (Narrative) Objective To propose a new framework, to
support the investigation and understanding of the pathobiology of DCM, AO Spine …

A functionalized collagen-I scaffold delivers microRNA 21-loaded exosomes for spinal cord injury repair

X Liu, L Zhang, Z Xu, X Xiong, Y Yu, H Wu, H Qiao… - Acta Biomaterialia, 2022 - Elsevier
MicroRNA (miRNA)-based therapies have shown great potential in the repair of spinal cord
injury (SCI). MicroRNA 21 (miR21) has been proven to have an essential protective effect on …

[HTML][HTML] Functional hydrogels as therapeutic tools for spinal cord injury: New perspectives on immunopharmacological interventions

CM Walsh, JK Wychowaniec, DF Brougham… - Pharmacology & …, 2022 - Elsevier
Spinal cord injury (SCI) is a complex medical and psychological challenge for which there is
no curative therapy currently available. Despite major progress in pharmacological and …

Mesenchymal stem cells in treatment of spinal cord injury and amyotrophic lateral sclerosis

E Sykova, D Cizkova, S Kubinova - Frontiers in cell and …, 2021 - frontiersin.org
Preclinical and clinical studies with various stem cells, their secretomes, and extracellular
vesicles (EVs) indicate their use as a promising strategy for the treatment of various …

The roles and applications of neural stem cells in spinal cord injury repair

W Guo, X Zhang, J Zhai, J Xue - Frontiers in Bioengineering and …, 2022 - frontiersin.org
Spinal cord injury (SCI), which has no current cure, places a severe burden on patients.
Stem cell-based therapies are considered promising in attempts to repair injured spinal …