The health benefits of exercise are well-recognized and are observed across multiple organ
systems. These beneficial effects enhance overall resilience, healthspan and longevity. The …

Objective Use of the frailty index to measure an accumulation of deficits has been proven a
valuable method for identifying elderly people at risk for increased vulnerability, disease …

Obesity and ageing place a tremendous strain on the global healthcare system. Age-related
sarcopenia is characterized by decreased muscular strength, decreased muscle quantity …

White adipose tissue (WAT) is an endocrine organ highly integrated in homeostasis and
capable of establishing ways of communicating and influencing multiple metabolic …

Exercise is an effective strategy for preventing and treating obesity and its related
cardiometabolic disorders, resulting in significant loss of body fat mass, white adipose tissue …

In the last few years, the muscular system has gained attention due to the discovery of the
muscle-secretome and its high potency for retaining or regaining health. These cytokines …

Background: Exercise therapy plays an important role in the prevention and treatment of
type 2 diabetes (T2DM). The mechanism of exercise therapy in the improvement of …

Irisin is a muscle-secreted hormone that is generated by cleavage of membrane protein
FNDC-5 (fibronectin type III domain-containing protein 5). Irisin is considered to be a …

Exercise is a well-known non-pharmacological intervention to improve brain functions,
including cognition, memory, and motor coordination. Contraction of skeletal muscles during …

The purposes of the present study were (1) to explore and compare the acute effects of high-
intensity interval training (HIIT) and moderate-intensity continuous exercise (MICE) on …