Western diets and chronic diseases

TE Adolph, H Tilg - Nature medicine, 2024 - nature.com
Abstract 'Westernization', which incorporates industrial, cultural and dietary trends, has
paralleled the rise of noncommunicable diseases across the globe. Today, the Western-style …

[HTML][HTML] Imprinting of the immune system by the microbiota early in life

Z Al Nabhani, G Eberl - Mucosal immunology, 2020 - Elsevier
The ontogeny and maturation of the immune system is modulated by the microbiota. During
fetal life, the mother's microbiota produces compounds that are transferred to the fetus and …

The oral-gut axis: Salivary and fecal microbiome dysbiosis in patients with inflammatory bowel disease

MMH Abdelbary, M Hatting, A Bott… - Frontiers in Cellular …, 2022 - frontiersin.org
Inflammatory bowel disease (IBD) is a group of chronic inflammatory disorders that fall into
two main categories: Crohn's disease (CD) and ulcerative colitis (UC). The gastrointestinal …

Orally Administrable H2S‐Scavenging Metal–Organic Framework Prepared by Co‐Flow Microfluidics for Comprehensive Restoration of Intestinal Milieu

Y Dou, P Liu, Z Ding, Y Zhou, H Jing, Y Ren… - Advanced …, 2023 - Wiley Online Library
Intestinal milieu disorders are strongly related to the occurrence of inflammatory bowel
diseases (IBDs), which results from mucosa destruction, epithelium disruption, and tight …

Gut microbiota-derived metabolite signature in suckling and weaned piglets

M Beaumont, L Cauquil, A Bertide, I Ahn… - Journal of proteome …, 2020 - ACS Publications
The gut microbiota plays a key role in intestinal development at the suckling-to-weaning
transition. The objective of this study was to analyze the production of metabolites by the gut …

Maternal fiber deprivation alters microbiota in offspring, resulting in low-grade inflammation and predisposition to obesity

J Zou, VL Ngo, Y Wang, Y Wang, AT Gewirtz - Cell host & microbe, 2023 - cell.com
Diet, especially fiber content, plays an important role in sustaining a healthy gut microbiota,
which promotes intestinal and metabolic health. Another major determinant of microbiota …

The influence of the western diet on microbiota and gastrointestinal immunity

V Las Heras, S Melgar, J MacSharry… - Annual Review of …, 2022 - annualreviews.org
Diet exerts a major influence upon host immune function and the gastrointestinal microbiota.
Although components of the human diet (including carbohydrates, fats, and proteins) are …

Transgenerational transmission of reproductive and metabolic dysfunction in the male progeny of polycystic ovary syndrome

S Risal, C Li, Q Luo, R Fornes, H Lu, G Eriksson… - Cell Reports …, 2023 - cell.com
The transgenerational maternal effects of polycystic ovary syndrome (PCOS) in female
progeny are being revealed. As there is evidence that a male equivalent of PCOS may …

Modified montmorillonite armed probiotics with enhanced on-site mucus-depleted intestinal colonization and H2S scavenging for colitis treatment

J Yang, S Ge, S Tan, H Liu, M Yang, W Liu… - Journal of Controlled …, 2024 - Elsevier
Inflammatory bowel diseases (IBD) are often associated with dysregulated gut microbiota
and excessive inflammatory microenvironment. Probiotic therapy combined with …

Gut microbial metabolite deoxycholic acid facilitates Th17 differentiation through modulating cholesterol biosynthesis and participates in high-fat diet-associated …

D Li, J Zhou, L Wang, Z Gong, H Le, Y Huang, C Xu… - Cell & Bioscience, 2023 - Springer
Background High-fat diet (HFD) is closely associated with the increased prevalence of
inflammatory bowel disease (IBD). Excessive gut microbial metabolite deoxycholic acid …